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A Design-Based Matching Framework for Staggered Adoption with Time-Varying Confounding

时变混杂下错位处理采用的基于设计匹配框架

Causal inference in longitudinal datasets has long been challenging due to dynamic treatment adoption and confounding by time-varying covariates. Prior work either fails to account for heterogeneity across treatment adoption cohorts and treatment timings or relies on modeling assumptions. In this paper, we develop a novel design-based framework for inference on group- and time-specific treatment effects in panel data with staggered treatment adoption. We establish…

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A Randomization-Based Method for Evaluating Time-Varying Treatment Effects

评价时变处理效应的随机化方法

Tests for paired censored outcomes have been extensively studied, with some justified in the context of randomization-based inference. These tests are primarily designed to detect an overall treatment effect across the entire follow-up period, providing limited insight into when the effect manifests and how it changes over time. In this article, we introduce new randomization-based tests for paired censored outcomes that enable both time-specific and long-term analysis of a…

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Mixing Samples to Address Weak Overlap in Causal Inference

通过混合样本应对因果推断中的弱重叠

In observational studies, the assumption of sufficient overlap (positivity) is fundamental for the identification and estimation of causal effects. Failing to account for this assumption yields inaccurate and potentially infeasible estimators. To address this issue, we introduce a simple yet novel approach, \textit{mixing}, which mitigates overlap violations by constructing a synthetic treated group that combines treated and control units. Our strategy offers three key…

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Absolute average and median treatment effects as causal estimands on metric spaces

度量空间上的绝对平均与中位处理效应

We define the notions of absolute average and median treatment effects as causal estimands on general metric spaces such as Riemannian manifolds, propose estimators using stratification, and prove several properties, including strong consistency. In the process, we also demonstrate the strong consistency of the weighted sample Fréchet means and geometric medians. Stratification allows these estimators to be utilized beyond the narrow constraints of a completely randomized…

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Differential recall bias in estimating treatment effects in observational studies

观察性研究中处理效应估计的差异性回忆偏差

Observational studies are frequently used to estimate the effect of an exposure or treatment on an outcome. To obtain an unbiased estimate of the treatment effect, it is crucial to measure the exposure accurately. A common type of exposure misclassification is recall bias, which occurs in retrospective cohort studies when study subjects may inaccurately recall their past exposure. Particularly challenging is differential recall bias in the context of self-reported binary…

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Local causal effects with continuous exposures: A matching estimator for the average causal derivative effect

连续暴露的局部因果效应:平均因果导数效应的匹配估计

The estimation of causal effects is a fundamental goal in the field of causal inference. However, it is challenging for various reasons. One reason is that the exposure (or treatment) is naturally continuous in many real-world scenarios. When dealing with continuous exposure, dichotomizing the exposure variable based on a pre-defined threshold may result in a biased understanding of causal relationships. In this paper, we propose a novel causal inference framework that can…

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Accounting for recall bias in case-control studies: a causal inference approach

病例对照研究中的回忆偏差:因果推断方法

A case-control study is designed to help determine if an exposure is associated with an outcome. However, since case-control studies are retrospective, they are often subject to recall bias. Recall bias can occur when study subjects do not remember previous events accurately. In this paper, we first define the estimand of interest: the causal odds ratio (COR) for a case-control study. Second, we develop estimation approaches for the COR and present estimates as a function of…

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