Heterogeneous Gene Network Estimation for Single-Cell Transcriptomic Data via a Joint Regularized Deep Neural Network
通过联合正则化深度神经网络估计单细胞异质基因网络
Estimation of intracellular gene networks has been a critical component of single-cell transcriptomic data analysis, which can provide crucial insights into the complex interplay between genes, facilitating the discovery of the biological basis of human life at single-cell resolution. Despite notable achievements, existing methodologies often falter in their practicality, primarily due to their narrow focus on simplistic linear relationships and inadequate handling of…