A Bayesian Functional Concurrent Zero-Inflated Dirichlet-Multinomial Regression Model with Application to Infant Microbiome
贝叶斯函数型同期零膨胀狄利克雷-多项回归模型及其在婴儿微生物组中的应用
The infant microbiome undergoes rapid changes in composition over time and is associated with long-term risks of conditions such as immune strength, allergy, asthma, and other health outcomes. Modeling the associations between exposures or treatments and microbial composition over time is essential for understanding the factors that drive these changes. Estimating these temporal dynamics has several challenges including: repeated measures, overdispersion, compositionality,…