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Graphical criteria for the identification of marginal causal effects in continuous-time survival and event-history analyses

连续时间生存与事件史分析中边际因果效应识别的图形准则

Abstract We consider continuous-time survival and event-history settings, where our aim is to graphically represent causal structures allowing us to characterize when a causal parameter is identified from observational data. This causal parameter is formalized as the effect on an outcome event of a (possibly hypothetical) intervention on the intensity of a treatment process. To establish identifiability, we propose novel graphical rules indicating whether the observed…

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Parameterizing and simulating from causal models

因果模型的参数化与模拟

Abstract Many statistical problems in causal inference involve a probability distribution other than the one from which data are actually observed; as an additional complication, the object of interest is often a marginal quantity of this other probability distribution. This creates many practical complications for statistical inference, even where the problem is non-parametrically identified. In particular, it is difficult to perform likelihood-based inference, or even to…

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Seconder of the Vote of thanks to Vansteelandt and Dukes and Contribution to the Discussion of ‘Assumption-Lean Inference for Generalised Linear Model Parameters’

《广义线性模型参数的弱假设推断》讨论与致谢附议

In my view, one of the most important contributions of the field of causal inference has been to place the target of inference, the desired estimand, at the centre of the analysis. The estimand is chosen in view of the research question, and typically reflects what decision problem we need to solve or what our ideal (target) trial would be. Crucially, the (causal) estimand is not automatically a parameter that happens to parametrise a chosen model. The role of models is…

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Separable Effects for Causal Inference in the Presence of Competing Events

存在竞争事件时用于因果推断的可分离效应

In time-to-event settings, the presence of competing events complicates the definition of causal effects. Here we propose the new separable effects to study the causal effect of a treatment on an event of interest. The separable direct effect is the treatment effect on the event of interest not mediated by its effect on the competing event. The separable indirect effect is the treatment effect on the event of interest only through its effect on the competing event. Similar…

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Graphical Models for Marked Point Processes Based on Local Independence

基于局部独立性的标记点过程图模型

Summary A new class of graphical models capturing the dependence structure of events that occur in time is proposed. The graphs represent so-called local independences, meaning that the intensities of certain types of events are independent of some (but not necessarilly all) events in the past. This dynamic concept of independence is asymmetric, similar to Granger non-causality, so the corresponding local independence graphs differ considerably from classical graphical…

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