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Causal Survival Forests with Negative Controls

结合负向控制的因果生存森林

We study heterogeneous treatment-effect (HTE) estimation in observational survival studies commonly associated with both censored outcomes and unmeasured confounding. We integrate causal survival forests (CSF) with negative controls (NC) from proximal causal inference and introduce Negative Control Causal Survival Forests (NC-CSF), a flexible nonparametric HTE learner for survival analysis. Our approach uses a loss that incorporates proxy variables and Neyman…

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Partial Identification under High-Dimensional Potential Outcomes and Confounders via Optimal Transport

利用最优传输对高维潜在结果与混杂因素进行部分识别

Partial identification provides informative causal guarantees when point identification is impossible, but existing approaches based on optimal transport (OT) become computationally and statistically intractable in high-dimensional settings. This limitation is particularly severe when both potential outcomes and confounders are high-dimensional, where classical OT-based bounds suffer from the curse of dimensionality and unfavorable convergence rates. To address this…

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Selective Randomization Inference for Adaptive Experiments

自适应实验的选择性随机化推断

Adaptive experiments use preliminary analyses of the data to inform further course of action and are commonly used in many disciplines including medical and social sciences. Because the null hypothesis and experimental design are data-dependent, it has long been recognized that statistical inference for adaptive experiments is not straightforward. Most existing methods only apply to specific adaptive designs and rely on strong assumptions. In this work, we propose selective…

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Estimation and Inference for Causal Explainability

因果可解释性的估计与推断

Understanding how much each variable contributes to an outcome is a central question across disciplines. A causal view of explainability is favorable for its ability in uncovering underlying mechanisms and generalizing to new contexts. Based on a family of causal explainability quantities, we develop methods for their estimation and inference. In particular, we construct a one-step correction estimator using semi-parametric efficiency theory, which explicitly leverages the…

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Statistical Inference in Causal Partial Identification with Smooth Densities

光滑密度下因果部分识别的统计推断

Many causal quantities are only partially identifiable due to the inherent missingness of potential outcomes, and the associated partial identification (PI) sets can be obtained by solving an optimal transport (OT) problem. Covariates often provide additional information about the potential outcomes and thus yield tighter PI sets, which can be obtained via conditional optimal transport (COT). However, COT-based PI set estimators are susceptible to the curse of dimensionality…

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Causal Partial Identification via Conditional Optimal Transport

通过条件最优输运实现因果部分识别

We study the estimation of causal estimand involving the joint distribution of treatment and control outcomes for a single unit. In typical causal inference settings, it is impossible to observe both outcomes simultaneously, which places our estimation within the domain of partial identification (PI). Pre-treatment covariates can substantially reduce estimation uncertainty by shrinking the partially identified set. Recent work has shown that covariate-assisted PI sets can be…

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Adaptive sample splitting for randomization tests

随机化检验的自适应样本分割

Randomization tests are widely used to generate finite-sample valid $p$-values for causal inference on experimental data. However, when applied to subgroup analysis, these tests may lack power due to small subgroup sizes. Incorporating a shared estimator of the conditional average treatment effect (CATE) can substantially improve power across subgroups but requires sample splitting to preserve validity. To this end, we quantify each unit's contribution to estimation and…

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Tightening Causal Bounds via Covariate-Aware Optimal Transport

通过纳入协变量的最优传输收紧因果效应界

Causal estimands can vary significantly depending on the relationship between outcomes in treatment and control groups, potentially leading to wide partial identification (PI) intervals that impede decision making. Incorporating covariates can substantially tighten these bounds, but requires determining the range of PI over probability models consistent with the joint distributions of observed covariates and outcomes in treatment and control groups. This problem is known to…

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Selective randomization inference for subgroup effects with continuous biomarkers

连续生物标志物亚组效应的选择性随机化推断

Randomization tests are a popular method for testing causal effects in clinical trials with finite-sample validity. In the presence of heterogeneous treatment effects, it is often of interest to select a subgroup that benefits from the treatment, frequently by choosing a cutoff for a continuous biomarker. However, selecting the cutoff and testing the effect on the same data may fail to control the type I error. To address this, we propose using "self-contained" methods for…

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Trustworthy assessment of heterogeneous treatment effect estimator

异质性处理效应估计器的可信评估

Accurate heterogeneous treatment effect (HTE) estimation is essential for personalized recommendations, making it important to evaluate and compare HTE estimators. Traditional assessment methods are inapplicable due to missing counterfactuals. Current HTE evaluation methods rely on additional estimation or matching on test data, often ignoring the uncertainty introduced and potentially leading to incorrect conclusions. We propose incorporating uncertainty quantification into…

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Bridging multiple worlds: multi-marginal optimal transport for causal partial-identification problem

连接多个潜在世界:因果部分识别的多边际最优传输方法

Under the prevalent potential outcome model in causal inference, each unit is associated with multiple potential outcomes but at most one of which is observed, leading to many causal quantities being only partially identified. The inherent missing data issue echoes the multi-marginal optimal transport (MOT) problem, where marginal distributions are known, but how the marginals couple to form the joint distribution is unavailable. In this paper, we cast the causal partial…

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Estimating Heterogeneous Treatment Effects for General Responses

一般响应变量的异质性处理效应估计

Heterogeneous treatment effect models allow us to compare treatments at subgroup and individual levels, and are of increasing popularity in applications like personalized medicine, advertising, and education. In this talk, we first survey different causal estimands used in practice, which focus on estimating the difference in conditional means. We then propose DINA, the difference in natural parameters, to quantify heterogeneous treatment effect in exponential families and…

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