U-learning for Prediction Inference via Combinatory Multi-Subsampling: With Applications to LASSO and Neural Networks
基于组合多重子抽样的U学习:面向LASSO与神经网络的预测推断
Epigenetic aging clocks play a pivotal role in estimating an individual's biological age through the examination of DNA methylation patterns at numerous CpG (Cytosine-phosphate-Guanine) sites within their genome. However, making valid inferences on predicted epigenetic ages, or more broadly, on predictions derived from high-dimensional inputs, presents challenges. We introduce a novel U-learning approach via combinatory multi-subsampling for making ensemble predictions and…