Informative Simultaneous Confidence Intervals for Graphical Group Sequential Test Procedures
图形化群序贯检验的信息性同时置信区间
Test procedures for multiple hypotheses in a group sequential clinical trial that control the family-wise error rate are considered. Several graphical group sequential tests suggested in the literature, which are special cases of Bonferroni-closure tests, are discussed. The focus is on the question of whether to consider at the current stage only the evidence of the current repeated p-value or the evidence over all repeated p-values from the previous stages. A new test…