The Complex Estimand of Clone-Censor-Weighting When Studying Treatment Initiation Windows
研究治疗启动时间窗时克隆—删失—加权法的复杂估计对象
Clone-censor-weighting (CCW) is an analytic method for studying treatment regimens that are indistinguishable from one another at baseline without relying on landmark dates or creating immortal person time. One particularly interesting CCW application is estimating outcomes when starting treatment within specific time windows in observational data (e.g., starting a treatment within 30 days of hospitalization). In such cases, CCW estimates something fairly complex. We show…