Improving the Estimation of Site-Specific Effects and their Distribution in Multisite Trials
改进多地点试验中地点特定效应及其分布的估计
In multisite trials, researchers are often interested in several inferential goals: estimating treatment effects for each site, ranking these effects, and studying their distribution. This study seeks to identify optimal methods for estimating these targets. Through a comprehensive simulation study, we assess two strategies and their combined effects: semiparametric modeling of the prior distribution, and alternative posterior summary methods tailored to minimize specific…