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GAUGER: Generalized Regression Adjustment via Graph-Weighted Exposure-Level Residualization for Design-Based Inference Under Interference

GAUGER:干扰下基于图加权暴露水平残差化的回归调整

Estimating causal effects under interference is a common problem in social science and economics. However, it is challenging due to the complex dependency structure induced by network connections. In this paper, we propose GAUGER, a Generalized regression Adjustment framework via Graph-weighted Exposure-level Residualization for design-based causal inference under general interference. We first reveal a surprising mismatch between accuracy and efficiency in this setting:…

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Estimating within-cluster and between-cluster spillover effects in randomized saturation designs

随机饱和度设计中簇内与簇间溢出效应的估计

Randomized saturation designs are two-stage experiments: they first randomly assign treatment probabilities over the clusters and then randomly assign the treatment to the units within the clusters. The existing literature on randomized saturation designs focuses on estimating within-cluster spillover effects by assuming away between-cluster spillover effects. However, the units may interact across clusters in many practical randomized saturation designs. A leading example…

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Estimating treatment effects with competing intercurrent events in randomized controlled trials

随机对照试验中存在竞争性伴发事件的处理效应估计

The analysis of randomized controlled trials is often complicated by intercurrent events (IEs) -- events that occur after treatment initiation and affect either the interpretation or existence of outcome measurements. Examples include treatment discontinuation or the use of additional medications. In two recent clinical trials for systemic lupus erythematosus with complications of IEs, we classify the IEs into two broad categories: effect-informative (e.g., treatment…

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Efficient Inference for Noisy LLM-as-a-Judge Evaluation

Large language models (LLMs) are increasingly used as automatic evaluators of generative AI outputs, a paradigm often referred to as "LLM-as-a-judge." In practice, LLM judges are imperfect predictions for the underlying truth and can exhibit systematic, non-random errors. Two main approaches have recently been proposed to address this issue: (i) direct measurementerror correction based on misclassification models such as Rogan-Gladen-style estimators, and (ii)…

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TERRA: A Transformer-Enabled Recursive R-learner for Longitudinal Heterogeneous Treatment Effect Estimation

TERRA:用于纵向异质性处理效应估计的 Transformer 递归 R 学习器

Accurately estimating heterogeneous treatment effects (HTE) in longitudinal settings is essential for personalized decision-making across healthcare, public policy, education, and digital marketing. However, time-varying interventions introduce many unique challenges, such as carryover effects, time-varying heterogeneity, and post-treatment bias, which are not addressed by standard HTE methods. To address these challenges, we introduce TERRA (Transformer-Enabled Recursive…

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Design-based causal inference in bipartite experiments

二部实验中基于设计的因果推断

Bipartite experiments arise in various fields, in which the treatments are randomized over one set of units, while the outcomes are measured over another separate set of units. However, existing methods often rely on strong model assumptions about the data-generating process. Under the potential outcomes formulation, we explore design-based causal inference in bipartite experiments under weak assumptions by leveraging the sparsity structure of the bipartite graph that…

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Principal Stratification with Continuous Post-Treatment Variables: Nonparametric Identification and Semiparametric Estimation

连续处理后变量的主层分层:非参数识别与半参数估计

Post-treatment variables often complicate causal inference. They appear in many scientific problems, including noncompliance, truncation by death, mediation, and surrogate endpoint evaluation. Principal stratification is a strategy to address these challenges by adjusting for the potential values of the post-treatment variables, defined as the principal strata. It allows for characterizing treatment effect heterogeneity across principal strata and unveiling the mechanism of…

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Flexible sensitivity analysis for causal inference in observational studies subject to unmeasured confounding

未测量混杂下观察性研究因果推断的灵活敏感性分析

Causal inference with observational studies often suffers from unmeasured confounding, yielding biased estimators based on the unconfoundedness assumption. Sensitivity analysis assesses how the causal conclusions change with respect to different degrees of unmeasured confounding. Most existing sensitivity analysis methods work well for specific types of statistical estimation or testing strategies. We propose a flexible sensitivity analysis framework that can deal with…

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