Covariate Adjustment in Randomized Experiments Motivated by Higher-Order Influence Functions
受高阶影响函数启发的随机实验协变量调整
Higher-Order Influence Functions (HOIF), developed in a series of papers over the past twenty years, are a fundamental theoretical device for constructing rate-optimal causal-effect estimators from observational studies. However, the value of HOIF for analyzing well-conducted randomized controlled trials (RCT) has not been explicitly explored. In the recent U.S. Food and Drug Administration and European Medicines Agency guidelines on the practice of covariate adjustment in…