Signature-Informed Selection Detection: A Novel Method for Multi-Locus Temporal Population Genetic Model with Recombination
基于路径签名的选择检测：含重组的多位点时间种群遗传模型
In population genetics, there is often interest in inferring selection coefficients. This task becomes more challenging if multiple linked selected loci are considered simultaneously. For such a situation, we propose a novel generalized Bayesian framework where we compute a scoring rule posterior for the selection coefficients in multi-locus temporal population genetics models. As we consider trajectories of allele frequencies over time as our data, we choose to use a…