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用于空间结构时间序列的拉普拉斯 P 样条分布滞后非线性模型AI 解读

Distributed lag non-linear models (DLNM) have gained popularity for modeling nonlinear lagged relationships between exposures and outcomes. When applied to spatially referenced data, these models must account for spatial dependence, a challenge that has yet to be thoroughly explored within the penalized DLNM framework. This gap is mainly due to the complex model structure and high computational demands, particularly when dealing with large spatio-temporal datasets. To…

适用于多种删失机制的生存数据灵活控制函数方法AI 解读

This paper addresses the problem of identifying and estimating the causal effect of a treatment in the presence of unmeasured confounding and various types of right-censoring. Examples of these censoring mechanisms are administrative censoring, competing risks and dependent censoring (e.g. loss to follow-up). Different parametric transformations are applied to each event time, resulting in a regression model with a more additive structure and error terms that are…