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因果推断中系统识别与联合分析多重偏差的路线图AI 解读

Observational studies examining causal effects rely on unverifiable assumptions, the violation of which can induce multiple biases. Quantitative bias analysis (QBA) methods examine the sensitivity of findings to such violations, generally, by producing estimates under alternative assumptions, incorporating external information. Although substantial guidance exists for implementing QBA, there is limited guidance on how to systematically determine the assumptions underlying a…

理想试验：在目标试验模拟与随机试验中平衡因果目标的相关性和可行性AI 解读

Causal inference is the goal of randomized trials and many observational studies. The first step in a formal causal inference framework is to define the causal estimand, and in both types of study this can be intuitively defined as the effect in an ideal trial: a hypothetical perfect randomized experiment (with representative sample, perfect adherence, etc.). The target trial framework is increasingly used for causal inference in observational studies, but clarity is lacking…