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心理测量检验：量化低信度后果并改进信度估计AI 解读

We introduce a set of consequence-based measures that quantify the misclassification arising from imperfect reliability in multi-item psychometric scales. Particular attention is given to the probability of individuals in extreme latent-trait percentiles being correctly identified from their observed scores. These cost functions provide a principled and interpretable way to characterise how inadequate reliability distorts classification and reduces the informational value of…

制药行业面板数据建模是否应考虑高阶自回归结构？AI 解读

Longitudinal data, often in the form of panel data, are commonly encountered in the pharmaceutical industry. However it is not always possible to fit an unstructured covariance matrix when using the Mixed Model for Repeated Measures (MMRM). Here we argue that high-order autoregressive models provide a useful framework when more general correlation structures, such as the unstructured and/or Toeplitz, are unfeasible. The autoregressive model of order one is often suggested…