A studentized permutation test for the treatment effect in individual participant data meta-analysis
个体参与者数据元分析中处理效应的学生化置换检验
Meta-analysis is a well-established tool used to combine data from several independent studies, each of which usually compares the effect of an experimental treatment with a control group. While meta-analyses are often performed using aggregated study summaries, they may also be conducted using individual participant data (IPD). Classical meta-analysis models may be generalized to handle continuous IPD by formulating them within a linear mixed model framework. IPD…