A joint QoL-Survival framework with debiased estimation under truncation by death
死亡截断下生活质量与生存的联合框架及去偏估计
Evaluating quality-of-life (QoL) outcomes in populations with high mortality risk is complicated by truncation by death, since QoL is undefined for individuals who do not survive to the planned measurement time. We propose a framework that jointly models the distribution of QoL and survival without extrapolating QoL beyond death. Inspired by multistate formulations, we extend the joint characterization of binary health states and mortality to continuous QoL outcomes. Because…