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用于高维纵向数据聚类的稀疏因子模型AI 解读

Recent advances in engineering technologies have enabled the collection of a large number of longitudinal features. This wealth of information presents unique opportunities for researchers to investigate the complex nature of diseases and uncover underlying disease mechanisms. However, analyzing such kind of data can be difficult due to its high dimensionality, heterogeneity and computational challenges. In this paper, we propose a Bayesian nonparametric mixture model for…

用于构建临床试验合成对照组的贝叶斯非参数共同原子回归AI 解读

The availability of electronic health records (EHR) has opened opportunities to supplement increasingly expensive and difficult to carry out randomized controlled trials (RCT) with evidence from readily available real world data. In this paper, we use EHR data to construct synthetic control arms for treatment-only single arm trials. We propose a novel nonparametric Bayesian common atoms mixture model that allows us to find equivalent population strata in the EHR and the…