Interpretational challenges of the Win Ratio in analyzing Hierarchical Composite Endpoints in Chronic Kidney Disease
慢性肾病分层复合终点分析中胜率比的解释难题
Win statistics based methods have gained traction as a method for analyzing Hierarchical Composite Endpoints (HCEs) in randomized clinical trials, particularly in cardiovascular and kidney disease research. HCEs offer several key advantages, including increased statistical power, mitigation of competing risks, and hierarchical ranking of clinical outcomes. While, as summary measures, the win ratio (WR) along with the Net Benefit (NB) and the Win Odds (WO) provide a…