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Statistical Performance Guarantee for Subgroup Identification with Generic Machine Learning

通用机器学习子群识别的统计性能保证

Across a wide array of disciplines, many researchers use machine learning (ML) algorithms to identify a subgroup of individuals who are likely to benefit from a treatment the most (``exceptional responders'') or those who are harmed by it. A common approach to this subgroup identification problem consists of two steps. First, researchers estimate the conditional average treatment effect (CATE) using an ML algorithm. Next, they use the estimated CATE to select those…

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Comment on "Generic machine learning inference on heterogeneous treatment effects in randomized experiments."

评《随机实验中异质处理效应的通用机器学习推断》

We analyze the split-sample robust inference (SSRI) methodology proposed by Chernozhukov, Demirer, Duflo, and Fernandez-Val (CDDF) for quantifying uncertainty in heterogeneous treatment effect estimation. While SSRI effectively accounts for randomness in data splitting, its computational cost can be prohibitive when combined with complex machine learning (ML) models. We present an alternative randomization inference (RI) approach that maintains SSRI's generality without…

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Neyman Meets Causal Machine Learning: Experimental Evaluation of Individualized Treatment Rules

Neyman 与因果机器学习:个体化处理规则的实验评估

A century ago, Neyman showed how to evaluate the efficacy of treatment using a randomized experiment under a minimal set of assumptions. This classical repeated sampling framework serves as a basis of routine experimental analyses conducted by today's scientists across disciplines. In this paper, we demonstrate that Neyman's methodology can also be used to experimentally evaluate the efficacy of individualized treatment rules (ITRs), which are derived by modern causal…

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Statistical Inference for Heterogeneous Treatment Effects Discovered by Generic Machine Learning in Randomized Experiments

随机实验中通用机器学习发现的异质性处理效应:统计推断

Researchers are increasingly turning to machine learning (ML) algorithms to investigate causal heterogeneity in randomized experiments. Despite their promise, ML algorithms may fail to accurately ascertain heterogeneous treatment effects under practical settings with many covariates and small sample size. In addition, the quantification of estimation uncertainty remains a challenge. We develop a general approach to statistical inference for heterogeneous treatment effects…

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Distributionally Robust Causal Inference with Observational Data

利用观测数据进行分布鲁棒因果推断

We consider the estimation of average treatment effects in observational studies and propose a new framework of robust causal inference with unobserved confounders. Our approach is based on distributionally robust optimization and proceeds in two steps. We first specify the maximal degree to which the distribution of unobserved potential outcomes may deviate from that of observed outcomes. We then derive sharp bounds on the average treatment effects under this assumption.…

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