Unlocking Insights: Enhanced Analysis of Covariance in General Factorial Designs through Multiple Contrast Tests under Variance Heteroscedasticity
异方差下一般析因设计的协方差分析:多重对比检验
A common goal in clinical trials is to conduct tests on estimated treatment effects adjusted for covariates such as age or sex. Analysis of Covariance (ANCOVA) is often used in these scenarios to test the global null hypothesis of no treatment effect using an $F$-test. However, in several samples, the $F$-test does not provide any information about individual null hypotheses and has strict assumptions such as variance homoscedasticity. We extend the method proposed by…