论文检索

权重且慢：理解不同目标总体下总体平均处理效应估计的变动AI 解读

Clinical study populations often differ meaningfully from the broader populations to which results are intended to generalize. Weighting methods such as inverse probability of sampling weights (IPSW) reweight study participants to resemble a target population, but the accuracy of these estimates depends heavily on how well the chosen population represents the population of substantive interest. We conduct a simulation study grounded in empirical covariate distributions from…

临床试验中利用外部对照：目标量、估计与假设AI 解读

It is increasingly common to augment randomized controlled trial with external controls from observational data, to evaluate the treatment effect of an intervention. Traditional approaches to treatment effect estimation involve ambiguous estimands and unrealistic or strong assumptions, such as mean exchangeability. We introduce a double-indexed notation for potential outcomes to define causal estimands transparently and clarify distinct sources of implicit bias. We show that…

利用重叠权重处理反事实生存函数估计中的极端倾向得分AI 解读

The inverse probability weighting approach is popular for evaluating treatment effects in observational studies, but extreme propensity scores could bias the estimator and induce excessive variance. Recently, the overlap weighting approach has been proposed to alleviate this problem, which smoothly down-weighs the subjects with extreme propensity scores. Although advantages of overlap weighting have been extensively demonstrated in literature with continuous and binary…