论文检索

倾向得分加权中的欠平滑LASSO与合成负对照暴露偏差检测AI 解读

The propensity score (PS) is often used to control for large numbers of covariates in high-dimensional healthcare database studies. The least absolute shrinkage and selection operator (LASSO) has become the most widely used tool for fitting large-scale PS models in these settings. LASSO uses L1 regularized regression to prevent overfitting by shrinking coefficients toward zero (setting some exactly to zero). The degree of regularization is typically selected using…

部分缺失混杂变量的高维多重插补：纳入自然语言处理辅助变量AI 解读

Multiple imputation (MI) models can be improved by including auxiliary covariates (AC), but their performance in high-dimensional data is not well understood. We aimed to develop and compare high-dimensional MI (HDMI) approaches using structured and natural language processing (NLP)-derived AC in studies with partially observed confounders. We conducted a plasmode simulation study using data from opioid vs. non-steroidal anti-inflammatory drug (NSAID) initiators (X) with…