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GenAI Powered Dynamic Causal Inference with Unstructured Data

生成式人工智能辅助的非结构化数据动态因果推断

A growing number of scholars seek to estimate causal effects of unstructured data such as text, images, and video. However, existing methods typically treat each object as a single, static observation. We develop a statistical framework for dynamic causal inference with unstructured data by leveraging generative artificial intelligence (GenAI) models. Our approach enables researchers to estimate the causal effects of sequences of treatment features, including their positions…

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Leveraging Generative Artificial Intelligence for Causal Inference with Unstructured Data

利用生成式人工智能对非结构化数据开展因果推断

We introduce GenAI-Powered Inference (GPI), a statistical framework for both causal and predictive inference using unstructured data, including text and images. GPI leverages open-source Generative Artificial Intelligence (GenAI) models---such as large language models and diffusion models---not only to generate unstructured data at scale but also to extract low-dimensional representations that are guaranteed to capture their underlying structure. Applying machine learning to…

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Estimating Heterogeneous Treatment Effects for Spatio-Temporal Causal Inference

时空因果推断中的异质性处理效应估计

Scholars from diverse fields increasingly rely on high-frequency spatio-temporal data. Yet, causal inference with these data remains challenging due to spatial spillover and temporal carryover effects. We develop methods to estimate heterogeneous treatment effects by allowing for arbitrary spatial and temporal causal dependencies. We focus on common settings where the treatment and outcomes are time-varying spatial point patterns and where moderators are either spatial or…

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Low-rank Covariate Balancing Estimators under Interference

存在单位间干扰时的低秩协变量平衡估计

A key methodological challenge in observational studies with interference between units is twofold: (1) each unit's outcome may depend on many others' treatments, and (2) treatment assignments may exhibit complex dependencies across units. We develop a general statistical framework for constructing robust causal effect estimators to address these challenges. We first show that, without restricting the patterns of interference, the standard inverse probability weighting (IPW)…

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Privacy-preserving Meta-analysis through Low-Rank Basis Hunting

通过低秩基函数搜寻实现保护隐私的元分析

A central challenge of meta-analysis is that the populations underlying existing studies often differ from the target population in unknown ways. We study the problem of predicting function-valued quantities, such as regression and conditional average treatment effect functions, for a new target population using only study-level covariates and study-specific function estimates. We propose MetaHunt, a new meta-analysis methodology based on a shared low-rank structure, in…

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Minimax Regret Estimation for Generalizing Heterogeneous Treatment Effects with Multisite Data

多地点异质性处理效应推广的极小极大遗憾估计

To test scientific theories and develop individualized treatment rules, researchers often wish to learn heterogeneous treatment effects that can be consistently found across diverse populations and contexts. We consider the problem of generalizing heterogeneous treatment effects (HTE) based on data from multiple sites. A key challenge is that a target population may differ from the source sites in unknown and unobservable ways. This means that the estimates from…

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Spatiotemporal causal inference with arbitrary spillover and carryover effects: Airstrikes and insurgent violence in the Iraq War

允许任意溢出与延续效应的时空因果推断:伊拉克战争中的空袭与叛乱暴力

Social scientists now routinely draw on high-frequency, high-granularity ''microlevel'' data to estimate the causal effects of subnational interventions. To date, most researchers aggregate these data into panels, often tied to large-scale administrative units. This approach has two limitations. First, data (over)aggregation obscures valuable spatial and temporal information, heightening the risk of mistaken inferences. Second, existing panel approaches either ignore spatial…

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Statistical Performance Guarantee for Subgroup Identification with Generic Machine Learning

通用机器学习子群识别的统计性能保证

Across a wide array of disciplines, many researchers use machine learning (ML) algorithms to identify a subgroup of individuals who are likely to benefit from a treatment the most (``exceptional responders'') or those who are harmed by it. A common approach to this subgroup identification problem consists of two steps. First, researchers estimate the conditional average treatment effect (CATE) using an ML algorithm. Next, they use the estimated CATE to select those…

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PanelMatch: Matching Methods for Causal Inference with Time-Series Cross-Section Data

PanelMatch:时间序列截面数据因果推断的匹配方法

Analyzing time-series cross-sectional (also known as longitudinal or panel) data is an important process across a number of fields, including the social sciences, economics, finance, and medicine. PanelMatch is an R package that implements a set of tools enabling researchers to apply matching methods for causal inference with time-series cross-sectional data. Relative to other commonly used methods for longitudinal analyses, like regression with fixed effects, the…

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Individualized Policy Evaluation and Learning under Clustered Network Interference

聚类网络干扰下的个体化政策评估与学习

Although there is now a large literature on policy evaluation and learning, much of the prior work assumes that the treatment assignment of one unit does not affect the outcome of another unit. Unfortunately, ignoring interference can lead to biased policy evaluation and ineffective learned policies. For example, treating influential individuals who have many friends can generate positive spillover effects, thereby improving the overall performance of an individualized…

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Longitudinal Causal Inference with Selective Eligibility

具有选择性资格的纵向因果推断

Dropout poses a significant challenge to causal inference in longitudinal studies with time-varying treatments. However, existing research does not simultaneously address dropout and time-varying treatments. We examine selective eligibility, an important yet overlooked source of non-ignorable dropout in such settings. This problem arises when a unit's prior treatment history influences its eligibility for subsequent treatments, a common scenario in medical and other…

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Comment on "Generic machine learning inference on heterogeneous treatment effects in randomized experiments."

评《随机实验中异质处理效应的通用机器学习推断》

We analyze the split-sample robust inference (SSRI) methodology proposed by Chernozhukov, Demirer, Duflo, and Fernandez-Val (CDDF) for quantifying uncertainty in heterogeneous treatment effect estimation. While SSRI effectively accounts for randomness in data splitting, its computational cost can be prohibitive when combined with complex machine learning (ML) models. We present an alternative randomization inference (RI) approach that maintains SSRI's generality without…

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Estimating Heterogeneous Causal Effects of High-Dimensional Treatments: Application to Conjoint Analysis

高维处理的异质性因果效应估计:联合分析应用

Estimation of heterogeneous treatment effects is an active area of research. Most of the existing methods, however, focus on estimating the conditional average treatment effects of a single, binary treatment given a set of pre-treatment covariates. In this paper, we propose a method to estimate the heterogeneous causal effects of high-dimensional treatments, which poses unique challenges in terms of estimation and interpretation. The proposed approach finds maximally…

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Safe Policy Learning under Regression Discontinuity Designs with Multiple Cutoffs

多阈值断点回归设计下的安全政策学习

The regression discontinuity (RD) design is widely used for program evaluation with observational data. The primary focus of the existing literature has been the estimation of the local average treatment effect at the existing treatment cutoff. In contrast, we consider policy learning under the RD design. Because the treatment assignment mechanism is deterministic, learning better treatment cutoffs requires extrapolation. We develop a robust optimization approach to finding…

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Priming bias versus post-treatment bias in experimental designs

实验设计中的启动偏误与处理后偏误

Conditioning on variables affected by treatment can induce post-treatment bias when estimating causal effects. Although this suggests that researchers should measure potential moderators before administering the treatment in an experiment, doing so may also bias causal effect estimation if the covariate measurement primes respondents to react differently to the treatment. This paper formally analyzes this trade-off between post-treatment and priming biases in three…

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Design-based inference for generalized network experiments with stochastic interventions

随机干预下广义网络实验的基于设计推断

A growing number of researchers are conducting randomized experiments to analyze causal relationships in network settings where units influence one another. A dominant methodology for analyzing these experiments is design-based, leveraging random treatment assignments as the basis for inference. In this paper, we generalize this design-based approach to accommodate complex experiments with a variety of causal estimands and different target populations. An important special…

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Neyman Meets Causal Machine Learning: Experimental Evaluation of Individualized Treatment Rules

Neyman 与因果机器学习:个体化处理规则的实验评估

A century ago, Neyman showed how to evaluate the efficacy of treatment using a randomized experiment under a minimal set of assumptions. This classical repeated sampling framework serves as a basis of routine experimental analyses conducted by today's scientists across disciplines. In this paper, we demonstrate that Neyman's methodology can also be used to experimentally evaluate the efficacy of individualized treatment rules (ITRs), which are derived by modern causal…

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Statistical Inference for Heterogeneous Treatment Effects Discovered by Generic Machine Learning in Randomized Experiments

随机实验中通用机器学习发现的异质性处理效应:统计推断

Researchers are increasingly turning to machine learning (ML) algorithms to investigate causal heterogeneity in randomized experiments. Despite their promise, ML algorithms may fail to accurately ascertain heterogeneous treatment effects under practical settings with many covariates and small sample size. In addition, the quantification of estimation uncertainty remains a challenge. We develop a general approach to statistical inference for heterogeneous treatment effects…

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Distributionally Robust Causal Inference with Observational Data

利用观测数据进行分布鲁棒因果推断

We consider the estimation of average treatment effects in observational studies and propose a new framework of robust causal inference with unobserved confounders. Our approach is based on distributionally robust optimization and proceeds in two steps. We first specify the maximal degree to which the distribution of unobserved potential outcomes may deviate from that of observed outcomes. We then derive sharp bounds on the average treatment effects under this assumption.…

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Using Machine Learning to Test Causal Hypotheses in Conjoint Analysis

利用机器学习检验联合分析中的因果假设

Conjoint analysis is a popular experimental design used to measure multidimensional preferences. Researchers examine how varying a factor of interest, while controlling for other relevant factors, influences decision-making. Currently, there exist two methodological approaches to analyzing data from a conjoint experiment. The first focuses on estimating the average marginal effects of each factor while averaging over the other factors. Although this allows for…

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Optimal Covariate Balancing Conditions in Propensity Score Estimation

倾向得分估计中的最优协变量平衡条件

Inverse probability of treatment weighting (IPTW) is a popular method for estimating the average treatment effect (ATE). However, empirical studies show that the IPTW estimators can be sensitive to the misspecification of the propensity score model. To address this problem, researchers have proposed to estimate propensity score by directly optimizing the balance of pre-treatment covariates. While these methods appear to empirically perform well, little is known about how the…

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Estimating Average Treatment Effects with Support Vector Machines

使用支持向量机估计平均处理效应

Support vector machine (SVM) is one of the most popular classification algorithms in the machine learning literature. We demonstrate that SVM can be used to balance covariates and estimate average causal effects under the unconfoundedness assumption. Specifically, we adapt the SVM classifier as a kernel-based weighting procedure that minimizes the maximum mean discrepancy between the treatment and control groups while simultaneously maximizing effective sample size. We also…

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