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粗化观测多状态过程状态占据概率的稳健估计AI 解读

We derive augmented inverse probability weighted estimators for occupation probabilities of multistate models under two levels of coarsening; right-censoring and baseline exposure. The key exchangeability assumption for identification is coarsening at random, while allowing for time-varying confounders, but not requiring Markov properties. Using existing techniques from causal inference and missing data literature, the derived estimators have highly desirable robustness and…

标记点过程数据的因果推断AI 解读

We define dynamic treatment regimes and associated potential outcomes for data described by marked point processes (MPPs). These definitions motivate MPP analogues of the commonly used consistency, exchangeability, and positivity conditions that are sufficient for identifying effects in MPP data structures. The conditions are formulated based on martingale theory, which allows us to derive explicit identifying assumptions for data described by stochastic processes. The…

连续时间生存与事件史分析中边际因果效应识别的图准则AI 解读

We consider continuous-time survival or more general event-history settings, where the aim is to infer the causal effect of a time-dependent treatment process. This is formalised as the effect on the outcome event of a (possibly hypothetical) intervention on the intensity of the treatment process, i.e. a stochastic intervention. To establish whether valid inference about the interventional situation can be drawn from typical observational, i.e. non-experimental, data we…

假想治疗加速：利用观察数据估计肾移植的因果效应AI 解读

Patients with end-stage kidney disease can expect to wait for several years before they receive a transplant, all the while their health deteriorates. How would the survival change if we managed to reduce these waiting times? To provide an answer, we present a continuous-time marginal structural model (MSM) of hypothetical scenarios in which the time until treatment is changed. In these scenarios, the treatment process is defined on a hypothetical time scale where time…