Nesting a Target Study within a Target Trial: A Framework for Evaluating Intervention Effects on Disparities
在目标试验中嵌入目标研究:评估干预对群体差距的影响
We present a novel framework (TS+TT) to nest a Target Study (TS) within a Target Trial (TT) for evaluating the effects of interventions on disparities. The TS component grounds the measurement of disparity in ethical assumptions, based on the concept of allowability, and anchors it to an explicit population within calendar time. It specifies an enrollment plan of stratified sampling of eligible persons to yield a sample where social groups are distributionally similar on…