Longitudinal Outcomes Truncated by Death: Causal Estimands and Bayesian Estimators
被死亡截断的纵向结局:因果估计目标与贝叶斯估计
In randomized controlled trials with longitudinal outcomes, death before the end of follow-up poses a fundamental challenge: after death, the outcome is no longer a real-valued measurement. This complicates the definition and interpretation of causal estimands, particularly when treatment may affect both survival and longitudinal outcomes. We review existing estimands for longitudinal outcomes truncated by death and clarify the assumptions required for their identification…