Semi-parametric estimation of biomarker age trends with endogenous medication use in longitudinal data
内生用药下纵向生物标志物年龄趋势的半参数估计
In cohort studies, non-random medication use can pose barriers to estimation of the natural history trend in a mean biomarker value (namely, the association between a predictor of interest and a biomarker outcome that would be observed in the absence of biomarker-specific treatment). Common causes of treatment and outcomes are often unmeasured, obscuring our ability to easily account for medication use with commonly invoked assumptions such as ignorability. Further, absent…