Simultaneous inference procedures for the comparison of multiple characteristics of two survival functions
比较两个生存函数多项特征的同时推断程序
Survival time is the primary endpoint of many randomized controlled trials, and a treatment effect is typically quantified by the hazard ratio under the assumption of proportional hazards. Awareness is increasing that in many settings this assumption is a-priori violated, e.g. due to delayed onset of drug effect. In these cases, interpretation of the hazard ratio estimate is ambiguous and statistical inference for alternative parameters to quantify a treatment effect is…