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BGM-IV: AI-Powered Bayesian Generative Modeling for Instrumental Variable Regression with High-Dimensional Covariates

BGM-IV:面向高维协变量工具变量回归的贝叶斯生成建模

Instrumental-variable (IV) regression enables causal estimation under endogeneity, but modern IV problems often involve nonlinear structural effects and high-dimensional covariates. Existing methods typically operate in observed or generic learned feature spaces, and they often yield point estimates without uncertainty quantification. We introduce BGM-IV, a Bayesian generative modeling approach that performs nonlinear IV regression through posterior inference in a causally…

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On the Graphical Rules for Recovering the Average Treatment Effect Under Selection Bias

选择偏差下恢复平均处理效应的图形规则

Selection bias is a major obstacle toward valid causal inference in epidemiology. Over the past decade, several graphical rules based on causal diagrams have been proposed as sufficient identification conditions for addressing selection bias and recovering causal effects. However, these simple graphical rules are typically coupled with specific identification strategies and estimators. In this article, we show two important cases of selection bias that fall outside the scope…

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What is Overlap Weighting, How Has it Evolved, and When to Use It for Causal Inference?

重叠加权是什么、如何发展及何时用于因果推断

The growing availability of large health databases has expanded the use of observational studies for comparative effectiveness research. Unlike randomized trials, observational studies must adjust for systematic differences in patient characteristics between treatment groups. Propensity score methods, including matching, weighting, stratification, and regression adjustment, address this issue by creating groups that are comparable with respect to measured covariates. Among…

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Constructing g-computation estimators: two case studies in selection bias

构造 g-computation 估计量:选择偏差的两个案例

G-computation is a useful estimation method that can be adapted to address various biases in epidemiology. However, these adaptations may not be obvious for some complex causal structures. This challenge is an example of the much wider issue of translating a causal diagram into a novel estimation strategy. To highlight these challenges, we consider two recent cases from the selection bias literature: treatment-induced selection and co-occurrence of biases that lack a joint…

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