Designing a quasi-experiment to study the clinical impact of adaptive risk prediction models
评估自适应风险预测模型临床影响的准实验设计
Clinical risk prediction is a valuable tool for guiding healthcare interventions toward those most likely to benefit. Yet, evaluating the pairing of a risk prediction model with an intervention using randomized controlled trials presents substantial challenges, making quasi-experimental designs an attractive alternatives. Existing designs, however, assume that both the model and the decision rules used to trigger interventions (typically a risk threshold) remain fixed. This…