Equivalence testing in pesticide risk assessment -- Evaluation and practical guidance for design, analysis and interpretation
农药风险评估中的等效性检验:设计、分析与解释
Harmful pesticide effects exceeding specific protection goals (SPG) may go undetected in underpowered experimental designs. Regulatory honeybee field studies have consistently failed to reach the statistical power required under European Food Safety Authority (EFSA) guidance, which may have caused approval of high-risk substances. Therefore, EFSA advised a shift from testing the null hypothesis of 'no effect' to equivalence testing. Under this approach, a pesticide is…