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二变量函数型因果发现的统计推断AI 解读

Causal discovery methods aim to determine the causal direction between variables using observational data. Functional causal discovery methods rely on structural and distributional assumptions to determine directionality but typically lack statistical inference. This paper reviews the statistical guarantees of existing functional causal discovery methods in theory, software, and applied use, highlighting a key gap: the absence of a unified inferential framework that applies…

结合专家与大语言模型的 g-computation：估计医院干预节省的时间AI 解读

Hospital quality improvement (QI) programs routinely face multiple candidate interventions to optimize hospital flow, but existing methods struggle to estimate and rank the causal effects of such interventions. This work focuses on one of the most standard hospital metrics, the average length of stay (LOS), and its causal estimand, the average time saved. To characterize this causal effect, qualitative approaches rely on expert judgment to map patient trajectories, making…

通过统计功效进行因果发现AI 解读

Causal discovery methods aim to infer causal direction from observational data. Functional causal discovery approaches use structural asymmetries to identify causal directionality but rely on strong modeling assumptions and provide limited tools for uncertainty quantification. We introduce Causal Discovery via Statistical Power (CDSP), a statistical inference framework that connects causal direction estimation with statistical power and enables uncertainty quantification.…

处理效应随时间变化时阶梯楔形试验检验功效的影响因素AI 解读

Stepped wedge cluster randomized trials (SW-CRTs) have historically been analyzed using immediate treatment (IT) models, which assume the effect of the treatment is immediate after treatment initiation and subsequently remains constant over time. However, recent research has shown that this assumption can lead to severely misleading results if treatment effects vary with exposure time, i.e. time since the intervention started. Models that account for time-varying treatment…

函数型因果发现的诊断工具AI 解读

Causal discovery methods aim to determine the causal direction between variables using observational data. Functional causal discovery methods, such as those based on the Linear Non-Gaussian Acyclic Model (LiNGAM), rely on structural and distributional assumptions to infer the causal direction. However, approaches for assessing causal discovery methods' performance as a function of sample size or the impact of assumption violations, inevitable in real-world scenarios, are…

处理效应随暴露时间变化时的阶梯楔形整群随机试验分析AI 解读

Stepped wedge cluster randomized controlled trials are typically analyzed using models that assume the full effect of the treatment is achieved instantaneously. We provide an analytical framework for scenarios in which the treatment effect varies as a function of exposure time (time since the start of treatment) and define the "effect curve" as the magnitude of the treatment effect on the linear predictor scale as a function of exposure time. The "time-averaged treatment…