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The synthetic instrument: From sparse association to sparse causation

合成工具变量:从稀疏关联到稀疏因果效应

In many observational studies, researchers are often interested in studying the effects of multiple exposures on a single outcome. Standard approaches for high-dimensional data such as the lasso assume the associations between the exposures and the outcome are sparse. These methods, however, do not estimate the causal effects in the presence of unmeasured confounding. In this paper, we consider an alternative approach that assumes the causal effects in view are sparse. We…

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Towards R-learner with Continuous Treatments

迈向连续处理的 R-learner

The R-learner is widely used in causal inference due to its flexibility and efficiency in estimating the conditional average treatment effect. However, extending the R-learner framework from binary to continuous treatments introduces a non-identifiability issue, as the functional zero constraint inherent to the conditional average treatment effect cannot be directly imposed in the R-loss under continuous treatments. To address this, we propose a two-step identification…

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Simultaneous Estimation of Multiple Treatment Effects from Observational Studies

从观测研究中同时估计多个处理效应

Unmeasured confounding presents a significant challenge in causal inference from observational studies. Classical approaches often rely on collecting proxy variables, such as instrumental variables. However, in applications where the effects of multiple treatments are of simultaneous interest, finding a sufficient number of proxy variables for consistent estimation of treatment effects can be challenging. Various methods in the literature exploit the structure of multiple…

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Stationarity of Manifold Time Series

流形时间序列的平稳性

In modern interdisciplinary research, manifold time series data have been garnering more attention. A critical question in analyzing such data is ``stationarity'', which reflects the underlying dynamic behavior and is crucial across various fields like cell biology, neuroscience and empirical finance. Yet, there has been an absence of a formal definition of stationarity that is tailored to manifold time series. This work bridges this gap by proposing the first definitions of…

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Fighting Noise with Noise: Causal Inference with Many Candidate Instruments

以噪声对抗噪声:大量候选工具变量下的因果推断

Instrumental variable methods provide useful tools for inferring causal effects in the presence of unmeasured confounding. To apply these methods with large-scale data sets, a major challenge is to find valid instruments from a possibly large candidate set. In practice, most of the candidate instruments are often not relevant for studying a particular exposure of interest. Moreover, not all relevant candidate instruments are valid as they may directly influence the outcome…

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Causal Inference on Distribution Functions

分布函数结果的因果推断

Understanding causal relationships is one of the most important goals of modern science. So far, the causal inference literature has focused almost exclusively on outcomes coming from the Euclidean space $\mathbb{R}^p$. However, it is increasingly common that complex datasets are best summarized as data points in non-linear spaces. In this paper, we present a novel framework of causal effects for outcomes from the Wasserstein space of cumulative distribution functions, which…

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