Bayesian design and analysis of two-arm cluster randomised trials using assurance: extension to binary outcomes and comparison of MCMC and INLA
基于保证概率的两组整群随机试验贝叶斯设计:二元结果及 MCMC 与 INLA 比较
The paper considers two different designs; a two-arm superiority cluster randomised controlled trial (RCT) with a continuous outcome, and a twoarm superiority cluster RCT with a binary outcome. From a Bayesian perspective, for the analysis of the trial we use a (generalised) linear mixed effects model. We summarise the inference for the treatment effect for a cluster RCT based on the posterior distribution. Based on this inference we use assurance to choose the sample size.…