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Clustered Switchback Designs for Experimentation Under Spatio-temporal Interference

时空干扰下用于实验的聚类切换设计

We consider experimentation in the presence of non-stationarity, inter-unit (spatial) interference, and carry-over effects (temporal interference), where we wish to estimate the global average treatment effect (GATE), the difference between average outcomes having exposed all units at all times to treatment or to control. We suppose spatial interference is described by a graph, where a unit's outcome depends on its neighborhood's treatments, and that temporal interference is…

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Surrogate-powered Causal Inference with Censored Outcomes

利用辅助事件信息进行删失结局的因果推断

Clinical trials with survival endpoints lose information when participants are censored before death is observed. We develop target-preserving estimators that use posttreatment disease history, such as recurrence or progression, to recover information lost to censoring for marginal survival and restricted mean survival effects. The difficulty is that the intermediate event is downstream of treatment: naive adjustment can change the causal estimand, and the useful information…

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Optimal Design under Interference, Homophily, and Robustness Trade-offs

干扰、同质性与稳健性权衡下的最优实验设计

To minimize the mean squared error (MSE) in global average treatment effect (GATE) estimation under network interference, a popular approach is to use a cluster-randomized design. However, in the presence of homophily, which is common in social networks, cluster randomization can instead increase the MSE. We develop a novel potential outcomes model that accounts for interference, homophily, and heterogeneous variation. In this setting, we establish a framework for optimizing…

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Low-order outcomes and clustered designs: combining design and analysis for causal inference under network interference

低阶结果模型与聚类设计:网络干扰下结合设计和分析的因果推断

Variance reduction for causal inference in the presence of network interference is often achieved through either outcome modeling, typically analyzed under unit-randomized Bernoulli designs, or clustered experimental designs, typically analyzed without strong parametric assumptions. In this work, we study the intersection of these two approaches and make the following threefold contributions. First, we present an estimator of the total treatment effect (or global average…

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Analysis of Two-Stage Rollout Designs with Clustering for Causal Inference under Network Interference

网络干扰下带聚类的两阶段逐步投放实验设计分析

Estimating causal effects under interference is pertinent to many real-world settings. Recent work with low-order potential outcomes models uses a rollout design to obtain unbiased estimators that require no interference network information. However, the required extrapolation can lead to prohibitively high variance. To address this, we propose a two-stage experiment that selects a sub-population in the first stage and restricts treatment rollout to this sub-population in…

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Exploiting Neighborhood Interference with Low Order Interactions under Unit Randomized Design

个体随机化设计下利用邻域干扰的低阶交互结构

Network interference, where the outcome of an individual is affected by the treatment assignment of those in their social network, is pervasive in real-world settings. However, it poses a challenge to estimating causal effects. We consider the task of estimating the total treatment effect (TTE), or the difference between the average outcomes of the population when everyone is treated versus when no one is, under network interference. Under a Bernoulli randomized design, we…

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Network Synthetic Interventions: A Causal Framework for Panel Data Under Network Interference

网络合成干预:网络干扰下的面板数据因果框架

We propose a generalization of the synthetic controls and synthetic interventions methodology to incorporate network interference. We consider the estimation of unit-specific potential outcomes from panel data in the presence of spillover across units and unobserved confounding. Key to our approach is a novel latent factor model that takes into account network interference and generalizes the factor models typically used in panel data settings. We propose an estimator,…

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Staggered Rollout Designs Enable Causal Inference Under Interference Without Network Knowledge

无需网络知识的干扰下因果推断:分阶段随机推广设计

Randomized experiments are widely used to estimate causal effects across a variety of domains. However, classical causal inference approaches rely on critical independence assumptions that are violated by network interference, when the treatment of one individual influences the outcomes of others. All existing approaches require at least approximate knowledge of the network, which may be unavailable and costly to collect. We consider the task of estimating the total…

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Estimating Total Treatment Effect in Randomized Experiments with Unknown Network Structure

网络结构未知时随机实验的总体处理效应估计

Randomized experiments are widely used to estimate the causal effects of a proposed treatment in many areas of science, from medicine and healthcare to the physical and biological sciences, from the social sciences to engineering, to public policy and to the technology industry at large. Here, we consider situations where classical methods for estimating the total treatment effect on a target population are considerably biased due to confounding network effects, i.e., the…

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