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切片 Lp 分布平衡方法AI 解读

A popular class of causal inference methods addresses confounding through weighting, which reweights treated and control groups to balance their covariate distributions without using outcome information, thereby preserving a design-based perspective. In this paper, we propose sliced $L^p$ distributional balancing (SLDB), a family indexed by $p\in[1,\infty)$ that measures imbalance by averaging squared $L^p$ distances between the cumulative distribution functions of…

乘法准工具变量模型AI 解读

We introduce the Multiplicative Quasi-Instrumental Variable (MQIV) model, a framework for causal inference with unmeasured confounding that leverages an instrument that may be imperfectly exogenous. We allow the candidate quasi-instrument to have a direct effect on the outcome not mediated by the treatment, thus violating the standard IV exclusion restriction. We establish nonparametric identification of the population average treatment effect on the treated (ATT) under a…

乘法工具变量模型AI 解读

The instrumental variable (IV) design is a common approach to address hidden confounding bias. For validity, an IV must impact the outcome only through its association with the treatment. In addition, IV identification has required a homogeneity condition such as monotonicity or no unmeasured common effect modifier between the additive effect of the treatment on the outcome, and that of the IV on the treatment. In this work, we introduce the Multiplicative Instrumental…

通用双重差分的非参数框架AI 解读

Difference-in-differences (DiD) is a popular approach to evaluate treatment effects in settings where both pre- and post-treatment measurements of the outcome are available. Despite its popularity, existing methods face important limitations. Specifically, they either: (i) only apply to continuous outcomes and the average treatment effect on the treated; (ii) are sensitive to the transformation of the outcome; (iii) rely on a no unmeasured confounding assumption given…

条件可分离效应的近端因果推断AI 解读

Scientists regularly pose questions about treatment effects on outcomes conditional on a post-treatment event. However, causal inference in such settings requires care, even in perfectly executed randomized experiments. Recently, the conditional separable effect (CSE) was proposed as an interventionist estimand that corresponds to scientifically meaningful questions in these settings. However, existing results for the CSE require no unmeasured confounding between the outcome…

因果推断中的分布平衡：基于特征函数距离的统一框架AI 解读

Weighting methods are essential tools for estimating causal effects in observational studies, with the goal of balancing pre-treatment covariates across treatment groups. Traditional approaches pursue this objective indirectly, for example, via inverse propensity score weighting or by matching a finite number of covariate moments, and therefore do not guarantee balance of the full joint covariate distributions. Recently, distributional balancing methods have emerged as…

可分二元治疗选择模型下的工具变量非参数推断AI 解读

Instrumental variable (IV) methods are widely used to infer treatment effects in the presence of unmeasured confounding. In this paper, we study nonparametric inference with an IV under a separable binary treatment choice model, which posits that the odds of the probability of taking the treatment, conditional on the instrument and the treatment-free potential outcome, factor into separable components for each variable. While nonparametric identification of smooth…

非随机缺失数据的乘法工具变量模型AI 解读

Instrumental variable (IV) methods offer a valuable approach to account for outcome data missing not-at-random. A valid missing data instrument is a measured factor which (i) predicts the nonresponse process and (ii) is independent of the outcome in the underlying population. For point identification, all existing IV methods for missing data including the celebrated Heckman selection model, a priori restrict the extent of selection bias on the outcome scale, therefore…

乘法工具变量模型下非线性反事实泛函的推断AI 解读

Instrumental variable (IV) methods play a central role in causal inference, particularly in settings where treatment assignment is confounded by unobserved variables. IV methods have been extensively developed in recent years and applied across diverse domains, from economics to epidemiology. In this work, we study the recently introduced multiplicative IV (MIV) model and demonstrate its utility for causal inference beyond the average treatment effect. In particular, we show…

单代理合成控制AI 解读

Synthetic control methods are widely used to estimate the treatment effect on a single treated unit in time-series settings. A common approach to estimate synthetic control weights is to regress the treated unit's pre-treatment outcome and covariates' time series measurements on those of untreated units via ordinary least squares. However, this approach can perform poorly if the pre-treatment fit is not near perfect, whether the weights are normalized or not. In this paper,…

基于回归的近端因果推断AI 解读

Negative controls are increasingly used to evaluate the presence of potential unmeasured confounding in observational studies. Beyond the use of negative controls to detect the presence of residual confounding, proximal causal inference (PCI) was recently proposed to de-bias confounded causal effect estimates, by leveraging a pair of treatment and outcome negative control or confounding proxy variables. While formal methods for statistical inference have been developed for…

单代理混杂控制AI 解读

Negative control variables are sometimes used in non-experimental studies to detect the presence of confounding by hidden factors. A negative control outcome (NCO) is an outcome that is influenced by unobserved confounders of the exposure effects on the outcome in view, but is not causally impacted by the exposure. Tchetgen Tchetgen (2013) introduced the Control Outcome Calibration Approach (COCA) as a formal NCO counterfactual method to detect and correct for residual…

流行病学因果推断中的通用双重差分AI 解读

Difference-in-differences is undoubtedly one of the most widely used methods for evaluating the causal effect of an intervention in observational (i.e., nonrandomized) settings. The approach is typically used when pre- and post-exposure outcome measurements are available, and one can reasonably assume that the association of the unobserved confounder with the outcome has the same absolute magnitude in the two exposure arms, and is constant over time; a so-called parallel…

整群随机实验中模型稳健且高效的协变量调整AI 解读

Cluster-randomized experiments are increasingly used to evaluate interventions in routine practice conditions, and researchers often adopt model-based methods with covariate adjustment in the statistical analyses. However, the validity of model-based covariate adjustment is unclear when the working models are misspecified, leading to ambiguity of estimands and risk of bias. In this article, we first adapt two conventional model-based methods, generalized estimating equations…

多层级研究中更高效的双重稳健非参数处理效应估计量AI 解读

When studying treatment effects in multilevel studies, investigators commonly use (semi-)parametric estimators, which make strong parametric assumptions about the outcome, the treatment, and/or the correlation structure between study units in a cluster. We propose a novel estimator of treatment effects that does not make such assumptions. Specifically, the new estimator is shown to be doubly robust, asymptotically Normal, and often more efficient than existing estimators,…