Patient stratification in multi-arm trials: a two-stage procedure with Bayesian profile regression
多臂试验中的患者分层:贝叶斯画像回归两阶段方法
Precision medicine is an emerging field that takes into account individual heterogeneity to inform better clinical practice. In clinical trials, the evaluation of treatment effect heterogeneity is an important component, and recently, many statistical methods have been proposed for stratifying patients into different subgroups based on such heterogeneity. However, the majority of existing methods developed for this purpose focus on the case with a dichotomous treatment and…