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Unbiased Treatment Effect Estimation under Network Interference via Neighborhood-Excluded Cross-Fitting

通过邻域排除交叉拟合实现网络干扰下的无偏处理效应估计

Without interference, cross-fitting enables flexible covariate adjustment while preserving finite-sample unbiasedness under independent unit-level randomization. Under network interference, out-of-sample prediction alone no longer guarantees unbiasedness: assignments entering evaluation-fold Horvitz--Thompson weights may also affect outcomes in the training sample, inducing dependence between fitted predictions and those weights. We develop neighborhood-excluded…

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Two-stage Least Squares with Clustered Data under the Local Average Treatment Effect Framework

局部平均处理效应框架下聚类数据的两阶段最小二乘

To estimate the causal effect of an endogenous treatment using clustered data, the canonical two-stage least squares (2sls) estimates a linear regression of the outcome on treatment status using an instrumental variable (IV) and conducts inference with cluster-robust standard errors. When both the treatment and the IV vary within clusters, an alternative two-stage least squares with fixed effects (2sfe) additionally includes cluster indicators in the regression, thereby…

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Two-stage least squares with treatment-covariate interactions for treatment effect heterogeneity

含处理与协变量交互项的两阶段最小二乘及处理效应异质性

Treatment effect heterogeneity with respect to covariates is common in instrumental variable (IV) analyses. An intuitive approach, which we call the interacted two-stage least squares (2sls), is to postulate a working linear model of the outcome on the treatment, covariates, and treatment-covariate interactions, and instrument it using the IV, covariates, and IV-covariate interactions. We clarify the causal interpretation of the interacted 2sls under the local average…

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Design-based theory for causal inference from adaptive experiments

自适应实验因果推断的设计本位理论

Adaptive designs dynamically update treatment probabilities using information accumulated during the experiment. Existing theory for causal inference from adaptive experiments primarily assumes the superpopulation framework with independent and identically distributed units, and may not apply when the distribution of units evolves over time. This paper makes two contributions. First, we extend the literature to the finite-population framework, which allows for possibly…

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Factorial Difference-in-Differences

析因双重差分

We formulate factorial difference-in-differences (FDID), a research design that extends canonical difference-in-differences (DID) to settings in which an event affects all units. In many panel data applications, researchers exploit cross-sectional variation in a baseline factor alongside temporal variation in the event, but the corresponding estimand is often implicit and the justification for applying the DID estimator remains unclear. We frame FDID as a factorial design…

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A randomization-based theory for preliminary testing of covariate balance in controlled trials

随机试验协变量平衡预检验的随机化理论

Randomized trials balance all covariates on average and provide the gold standard for estimating treatment effects. Chance imbalances nevertheless exist more or less in realized treatment allocations and intrigue an important question: what should we do in case the treatment groups differ with respect to some important baseline characteristics? A common strategy is to conduct a {\it preliminary test} of the balance of baseline covariates after randomization, and invoke…

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No star is good news: A unified look at rerandomization based on $p$-values from covariate balance tests

没有显著星号是好消息:基于协变量平衡检验 p 值的再随机化

Modern social and biomedical scientific publications require the reporting of covariate balance tables with not only covariate means by treatment group but also the associated $p$-values from significance tests of their differences. The practical need to avoid small $p$-values renders balance check and rerandomization by hypothesis testing standards an attractive tool for improving covariate balance in randomized experiments. Despite the intuitiveness of such practice and…

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Covariate adjustment in multi-armed, possibly factorial experiments

多处理臂及析因实验中的协变量调整

Randomized experiments are the gold standard for causal inference, and justify simple comparisons across treatment groups. Regression adjustment provides a convenient way to incorporate covariate information for additional efficiency. This article provides a unified account of its utility for improving estimation efficiency in multi-armed experiments. We start with the commonly used additive and fully interacted models for regression adjustment, and clarify the trade-offs…

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Rerandomization and covariate adjustment in split-plot designs

裂区设计中的再随机化与协变量调整

The split-plot design arises from agricultural sciences with experimental units, also known as subplots, nested within groups known as whole plots. It assigns the whole-plot intervention by a cluster randomization at the whole-plot level and assigns the subplot intervention by a stratified randomization at the subplot level. The randomization mechanism guarantees covariate balance on average at both the whole-plot and subplot levels, and ensures consistent inference of the…

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Regression-based causal inference with factorial experiments: estimands, model specifications, and design-based properties

析因实验的回归因果推断:目标量、模型设定与设计性质

Factorial designs are widely used due to their ability to accommodate multiple factors simultaneously. The factor-based regression with main effects and some interactions is the dominant strategy for downstream data analysis, delivering point estimators and standard errors via one single regression. Justification of these convenient estimators from the design-based perspective requires quantifying their sampling properties under the assignment mechanism conditioning on the…

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Reconciling design-based and model-based causal inferences for split-plot experiments

协调裂区试验中的设计型与模型型因果推断

The split-plot design assigns different interventions at the whole-plot and sub-plot levels, respectively, and induces a group structure on the final treatment assignments. A common strategy is to use the OLS fit of the outcome on the treatment indicators coupled with the robust standard errors clustered at the whole-plot level. It does not give consistent estimator for the causal effects of interest when the whole-plot sizes vary. Another common strategy is to fit the…

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To adjust or not to adjust? Estimating the average treatment effect in randomized experiments with missing covariates

调整还是不调整:协变量缺失的随机实验中平均处理效应估计

Complete randomization allows for consistent estimation of the average treatment effect based on the difference in means of the outcomes without strong modeling assumptions on the outcome-generating process. Appropriate use of the pretreatment covariates can further improve the estimation efficiency. However, missingness in covariates is common in experiments and raises an important question: should we adjust for covariates subject to missingness, and if so, how? The…

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