Optimal Study Designs for Cluster Randomised Trials: An Overview of Methods and Results
整群随机试验最优设计:方法与结果概览
There are multiple cluster randomised trial designs that vary in when the clusters cross between control and intervention states, when observations are made within clusters, and how many observations are made at that time point. Identifying the most efficient study design is complex though, owing to the correlation between observations within clusters and over time. In this article, we present a review of statistical and computational methods for identifying optimal cluster…