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提高检验功效的统一自适应富集设计AI 解读

Randomized controlled trials (RCTs) are the gold standard for evaluating treatment effects, but fixed eligibility criteria and enrollment decisions can be inefficient, especially when treatment effects vary across patient subpopulations. Adaptive enrichment trials update enrollment using interim data to improve efficiency. Enrichment methods are developed for two settings: prespecified subgroups, and continuous covariates where enrollment is guided by a learned cutoff. Many…

存在预期行为时处理效应的界限AI 解读

In program evaluations, units can often anticipate the implementation of a new policy before it occurs. Such anticipatory behavior can lead to units' outcomes becoming dependent on their future treatment assignments. In this paper, I employ a potential-outcomes framework to analyze the treatment effect with anticipation. I start with a classical difference-in-differences model with two time periods and provide identified sets with easy-to-implement estimation and inference…