A unified framework for estimating direct causal effect under spatial confounding and interference, with the R package spaci
空间混杂与干扰下直接因果效应估计的统一框架及 R 包 spaciAI 解读 ↓
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空间混杂与干扰下直接因果效应估计的统一框架及 R 包 spaciAI 解读 ↓
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Estimating causal effects is challenging with observational data due to the lack of exchangeability, and is further complicated with spatial data. In real-life applications such as agricultural and environmental studies, unobserved spatial factors (spatial confounding, SC) and interactions of units in nearby locations (spatial interference, SI) commonly occur jointly, yet existing parametric methods address them separately. We develop a unified framework that treats both simultaneously. We first define the estimand precisely and give an identification result. We then study two estimators. The matching estimator iDAPS integrates neighbourhood exposure and spatial proximity into propensity score matching with balance-optimised weights. We prove a variogram bias bound showing its confounding bias is controlled by the spatial variability of the confounder at the matched distance; this justifies the composite metric, yields a consistency result, and provides a computable diagnostic. The doubly robust estimator recoverU+ augments the propensity and outcome models with the recovered confounder and the exposure; we prove it is doubly robust up to an explicit residual bias from the unrecoverable confounder component. We show that independence-based standard errors are anticonservative under spatial dependence; we provide spatial heteroskedasticity and autocorrelation consistent (HAC), block-bootstrap, and randomisation-based alternatives whose calibration we verify. Every theoretical result is validated numerically. Estimating the effect of selective catalytic and non-catalytic reduction (SCR/SNCR) technologies on ambient ozone reveals no evidence of ozone reduction, while a naive analysis would have delivered a confidently wrong sign. All methods are implemented in the developed open-source R package spaci.
网络干扰下因果推断模型设定的随机化检验
Analysis of experimental data becomes challenging when the underlying population is connected by a network. Exposure mapping is a common tool in the literature for defining and estimating spillover effects. These mappings reduce the dimensionality of the estimand, thereby facilitating identifiability. It is assumed that this mapping is correctly specified, leaving the choice of the exposure mapping to the analyst. This makes estimators of the spillover effect, such as the…
网络干扰下因果推断的线性模型
In causal inference, interference occurs when the treatment of one unit may affect the outcomes of other units. The goal of this work is to serve as a guide to the use of linear outcome modeling for estimating causal effects in settings where interference may pose a challenge to identification and estimation, such as spatial and network data. We demonstrate that, under a linear model, causal effects of binary and continuous treatments can be identified in terms of regression…
因果推断的设计型理论
Causal inference, as a major research area in statistics and data science, plays a central role across diverse fields such as medicine, economics, education, and the social sciences. Design-based causal inference begins with randomized experiments and emphasizes conducting statistical inference by leveraging the known randomization mechanism, thereby enabling identification and estimation of causal effects under weak model dependence. Grounded in the seminal works of Fisher…
样本单位数为一时的随机化推断
Summary For decades, $ N $-of-1 experiments, where a unit serves as its own control and treatment in different time windows, have been used in certain medical contexts. However, due to effects that accumulate over long time windows and interventions that have complex evolution, a lack of robust inference tools has limited the widespread applicability of such $ N $-of-1 designs. This work combines techniques from experimental design in causal inference and system…
利用双重负对照识别与估计未观测网络混杂下的因果同伴效应
Scientists have been interested in estimating causal peer effects to understand how people's behaviors are affected by their network peers. However, it is well known that identification and estimation of causal peer effects are challenging in observational studies for two reasons. The first is the identification challenge due to unmeasured network confounding, for example, homophily bias and contextual confounding. The second issue is network dependence of observations,…
复杂(准)实验设计下的简单标准误
We develop standard errors for estimates of causal effects in settings where the distribution of treatment exposures is known but potentially exhibits complicated dependence patterns across units. Such dependence arises, for example, in settings with spillovers/interference across units or when the treatment assignment is spatially correlated. Our variance estimator generalizes several properties of the Neyman variance estimator for completely randomized experiments to…