Hierarchical Probabilistic Principal Component Analysis of Longitudinal Data
纵向数据的层级概率主成分分析AI 解读 ↓
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纵向数据的层级概率主成分分析AI 解读 ↓
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In many longitudinal studies, a large number of variables are measured repeatedly over time, with substantial missing data. Existing methods, such as probabilistic principal component analysis (PPCA), are ill-equipped to handle such incomplete, high-dimensional longitudinal data, as they fail to account for the nested sources of variation and temporal dependency inherent in repeated measures. We introduce hierarchical probabilistic principal component analysis (HPPCA), a two-level probabilistic factor model that explicitly separates between-subject variance from time-varying within-subject dynamics. The within-subject latent factors are modeled by a Gaussian process. We develop an EM algorithm to handle missing data and flexible covariance kernels, accelerated by computationally efficient initializers. Simulation studies demonstrated that HPPCA robustly recovers model parameters subspaces and substantially outperforms both standard PPCA and multivariate functional PCA in imputation accuracy, even under heavy missingness and model misspecification. An application to the long COVID symptoms in the Researching COVID to Enhance Recovery adult cohort revealed that HPPCA effectively captured the data's hierarchical structure and its learned features significantly improved the prediction of clinical outcomes and the recovery of masked clinical records compared to exisiting methods.
高维交互固定效应下的双重机器学习
Factor structures are central to empirical work in economics and finance, and are usually used to model time-varying unobserved heterogeneity through interactive fixed effects (IFE). Existing IFE estimators rest on low-dimensional and linear specifications in the covariates, assumptions which are increasingly restrictive in applications drawing on rich datasets with controls of unknown functional form. This paper develops a Double Machine Learning estimator for the…
具有时变潜在分组结构的面板数据模型
This paper considers a linear panel model with interactive fixed effects and unobserved individual and time heterogeneities that are captured by some latent group structures and an unknown structural break, respectively. To enhance realism, the model may have different numbers of groups and/or different group memberships before and after the break. With preliminary nuclear norm regularized estimation followed by row- and column-wise linear regressions, we estimate the break…
具有异质性的非参数时变面板模型
Since Bai (2009, Econometrica 77, 1229–1279), considerable extensions have been made to panel data models with interactive fixed effects (IFEs). However, little work has been conducted to understand the associated iterative algorithm, which, to the best of our knowledge, is the most commonly adopted approach in this line of research. In this paper, we refine the algorithm of panel data models with IFEs using the nuclear-norm penalization method and duple least-squares (DLS)…
具有时变潜在分组结构的面板数据模型
This paper considers a linear panel model with interactive fixed effects and unobserved individual and time heterogeneities that are captured by some latent group structures and an unknown structural break, respectively. To enhance realism the model may have different numbers of groups and/or different group memberships before and after the break. With the preliminary nuclear-norm-regularized estimation followed by row- and column-wise linear regressions, we estimate the…
纵向数据的超高维分位数回归:血压分析应用
Despite major advances in research and treatment, identifying important genotype risk factors for high blood pressure remains challenging. Traditional genome-wide association studies (GWAS) focus on one single nucleotide polymorphism (SNP) at a time. We aim to select among over half a million SNPs along with time-varying phenotype variables via simultaneous modeling and variable selection, focusing on the most dangerous blood pressure levels at high quantiles. Taking…
固定时间维度下含随机交互效应与多重结构突变的面板模型估计
In this article, we propose a new estimator of panel data models with random interactive effects and multiple structural breaks that is suitable when the number of time periods, T, is fixed and only the number of cross-sectional units, N, is large. This is done by viewing the determination of the breaks as a shrinkage problem, and to estimate both the regression coefficients, and the number of breaks and their locations by applying a version of the Lasso approach. We show…