Causal survival embeddings: non-parametric counterfactual inference under censoring
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因果生存嵌入:删失下的非参数反事实推断AI 解读 ↓
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Model-free time-to-event regression under confounding presents challenges due to biases introduced by causal and censoring sampling mechanisms. This phenomenology poses problems for classical non-parametric estimators like Beran's or the k-nearest neighbours algorithm. In this study, we propose a natural framework that leverages the structure of reproducing kernel Hilbert spaces (RKHS) and, specifically, the concept of kernel mean embedding to address these limitations. Our framework has the potential to enable statistical counterfactual modeling, including counterfactual prediction and hypothesis testing, under right-censoring schemes. Through simulations and an application to the SPRINT trial, we demonstrate the practical effectiveness of our method, yielding coherent results when compared to parallel analyses in existing literature. We also provide a theoretical analysis of our estimator through an RKHS-valued empirical process. Our approach offers a novel tool for performing counterfactual survival estimation in observational studies with incomplete information. It can also be complemented by state-of-the-art algorithms based on semi-parametric and parametric models.
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We study target-population distributional and quantile treatment effects when a source study observes treatment and post-treatment surrogates for all source units but observes a long-run primary outcome only for a validation subset, while the target population contributes only baseline covariates. The target estimands are transported counterfactual distribution functions $ψ_a(y)=P(Y^a\le y\mid R=0)$, their quantiles $q_a(τ)$, and the quantile treatment effect $Δ(τ)=q_1(τ)-q_0(τ)$…
可微 Hilbert 空间值参数的一步估计
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We present estimators for smooth Hilbert-valued parameters, where smoothness is characterized by a pathwise differentiability condition. When the parameter space is a reproducing kernel Hilbert space, we provide a means to obtain efficient, root-n rate estimators and corresponding confidence sets. These estimators correspond to generalizations of cross-fitted one-step estimators based on Hilbert-valued efficient influence functions. We give theoretical guarantees even when…
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I propose kernel ridge regression estimators for nonparametric dose response curves and semiparametric treatment effects in the setting where an analyst has access to a selected sample rather than a random sample; only for select observations, the outcome is observed. I assume selection is as good as random conditional on treatment and a sufficiently rich set of observed covariates, where the covariates are allowed to cause treatment or be caused by treatment -- an extension…
中介与时变剂量反应曲线的序贯核嵌入
We propose simple nonparametric estimators for mediated and time-varying dose response curves based on kernel ridge regression. By embedding Pearl's mediation formula and Robins' g-formula with kernels, we allow treatments, mediators, and covariates to be continuous in general spaces, and also allow for nonlinear treatment-confounder feedback. Our key innovation is a reproducing kernel Hilbert space technique called sequential kernel embedding, which we use to construct…
条件分布处理效应:双重稳健估计与检验
Beyond conditional average treatment effects, treatments may impact the entire outcome distribution in covariate-dependent ways, for example, by altering the variance or tail risks for specific subpopulations. We propose a novel estimand to capture such conditional distributional treatment effects, and develop a doubly robust estimator that is minimax optimal in the local asymptotic sense. Using this, we develop a test for the global homogeneity of conditional potential…