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Asymptotic optimality and efficient computation of the leave-subject-out cross-validation

留受试者交叉验证的渐近最优性与高效计算

Although the leave-subject-out cross-validation (CV) has been widely used in practice for tuning parameter selection for various nonparametric and semiparametric models of longitudinal data, its theoretical property is unknown and solving the associated optimization problem is computationally expensive, especially when there are multiple tuning parameters. In this paper, by focusing on the penalized spline method, we show that the leave-subject-out CV is optimal in the sense…

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The transfer principle: A tool for complete case analysis

转移原理:完整案例分析的工具

This paper gives a general method for deriving limiting distributions of complete case statistics for missing data models from corresponding results for the model where all data are observed. This provides a convenient tool for obtaining the asymptotic behavior of complete case versions of established full data methods without lengthy proofs. The methodology is illustrated by analyzing three inference procedures for partially linear regression models with responses missing…

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Independent component analysis via nonparametric maximum likelihood estimation

基于非参数极大似然估计的独立成分分析

Independent Component Analysis (ICA) models are very popular semiparametric models in which we observe independent copies of a random vector $X=AS$, where $A$ is a non-singular matrix and $S$ has independent components. We propose a new way of estimating the unmixing matrix $W=A^{-1}$ and the marginal distributions of the components of $S$ using nonparametric maximum likelihood. Specifically, we study the projection of the empirical distribution onto the subset of ICA…

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Two-step spline estimating equations for generalized additive partially linear models with large cluster sizes

大簇样本下广义可加部分线性模型的两步样条估计方程

We propose a two-step estimating procedure for generalized additive partially linear models with clustered data using estimating equations. Our proposed method applies to the case that the number of observations per cluster is allowed to increase with the number of independent subjects. We establish oracle properties for the two-step estimator of each function component such that it performs as well as the univariate function estimator by assuming that the parametric vector…

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Optimal two-stage procedures for estimating location and size of the maximum of a multivariate regression function

估计多元回归函数最大值位置与大小的最优两阶段程序

We propose a two-stage procedure for estimating the location $\mathbf{\mu}$ and size $M$ of the maximum of a smooth $d$-variate regression function $f$. In the first stage, a preliminary estimator of $\mathbf{\mu}$ obtained from a standard nonparametric smoothing method is used. At the second stage, we “zoom-in” near the vicinity of the preliminary estimator and make further observations at some design points in that vicinity. We fit an appropriate polynomial regression…

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Parametric estimation. Finite sample theory

参数估计的有限样本理论

The paper aims at reconsidering the famous Le Cam LAN theory. The main features of the approach which make it different from the classical one are as follows: (1) the study is nonasymptotic, that is, the sample size is fixed and does not tend to infinity; (2) the parametric assumption is possibly misspecified and the underlying data distribution can lie beyond the given parametric family. These two features enable to bridge the gap between parametric and nonparametric theory…

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Nonparametric Bayesian modelling of monotone preferences for discrete choice experiments

离散选择实验中单调偏好的非参数贝叶斯建模

Discrete choice experiments are widely used to learn about the distribution of individual preferences for product attributes. Such experiments are often designed and conducted deliberately for the purpose of designing new products. There is a long-standing literature on nonparametric and Bayesian modelling of preferences for the study of consumer choice when there is a market for each product, but this work does not apply when such markets fail to exist as is the case with…

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A class of adaptive importance sampling weighted EM algorithms for efficient and robust posterior and predictive simulation

用于后验与预测模拟的自适应重要性加权 EM 算法

A class of adaptive sampling methods is introduced for efficient posterior and predictive simulation. The proposed methods are robust in the sense that they can handle target distributions that exhibit non-elliptical shapes such as multimodality and skewness. The basic method makes use of sequences of importance weighted Expectation Maximization steps in order to efficiently construct a mixture of Student-t densities that approximates accurately the target…

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Testing for Gene–Environment and Gene–Gene Interactions Under Monotonicity Constraints

单调性约束下的基因—环境与基因—基因交互检验

Recent genome-wide association studies (GWASs) designed to detect the main effects of genetic markers have had considerable success with many findings validated by replication studies. However, relatively few findings of gene–gene or gene–environment interactions have been successfully reproduced. Besides the main issues associated with insufficient sample size in current studies, a complication is that interactions that rank high based on p-values often correspond to…

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Nonparametric Estimation for Censored Mixture Data With Application to the Cooperative Huntington’s Observational Research Trial

删失混合数据的非参数估计及亨廷顿病观察研究应用

This work presents methods for estimating genotype-specific distributions from genetic epidemiology studies where the event times are subject to right censoring, the genotypes are not directly observed, and the data arise from a mixture of scientifically meaningful subpopulations. Examples of such studies include kin-cohort studies and quantitative trait locus (QTL) studies. Current methods for analyzing censored mixture data include two types of nonparametric maximum…

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A Nonparametric Regression Model With Tree-Structured Response

树结构响应的非参数回归模型

Developments in science and technology over the last two decades has motivated the study of complex data objects. In this article, we consider the topological properties of a population of tree-structured objects. Our interest centers on modeling the relationship between a tree-structured response and other covariates. For tree-structured objects, this poses serious challenges since most regression methods rely on linear operations in Euclidean space. We generalize the…

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SURE Estimates for a Heteroscedastic Hierarchical Model

异方差层级模型中的 SURE 估计

Hierarchical models are extensively studied and widely used in statistics and many other scientific areas. They provide an effective tool for combining information from similar resources and achieving partial pooling of inference. Since the seminal work by James and Stein (1961 James, W. and Stein, C. M. 1961. “Estimation With Quadratic Loss,”. Proceedings of the 4th Berkeley Symposium on Probability and Statistics, I: 367–379. [Google Scholar]) and Stein (1962 Stein, C. M.…

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Landmark Prediction of Long-Term Survival Incorporating Short-Term Event Time Information

纳入短期事件时间信息的长期生存 Landmark 预测

In recent years, a wide range of markers have become available as potential tools to predict risk or progression of disease. In addition to such biological and genetic markers, short term outcome information may be useful in predicting long term disease outcomes. When such information is available, it would be desirable to combine this along with predictive markers to improve the prediction of long term survival. Most existing methods for incorporating censored short term…

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AdaptSPEC: Adaptive Spectral Estimation for Nonstationary Time Series

AdaptSPEC:非平稳时间序列的自适应谱估计

We propose a method for analyzing possibly nonstationary time series by adaptively dividing the time series into an unknown but finite number of segments and estimating the corresponding local spectra by smoothing splines. The model is formulated in a Bayesian framework, and the estimation relies on reversible jump Markov chain Monte Carlo (RJMCMC) methods. For a given segmentation of the time series, the likelihood function is approximated via a product of local Whittle…

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A Semiparametric Change-Point Regression Model for Longitudinal Observations

纵向观测的半参数变点回归模型

Many longitudinal studies involve relating an outcome process to a set of possibly time-varying covariates, giving rise to the usual regression models for longitudinal data. When the purpose of the study is to investigate the covariate effects when experimental environment undergoes abrupt changes or to locate the periods with different levels of covariate effects, a simple and easy-to-interpret approach is to introduce change-points in regression coefficients. In this…

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Direct Simultaneous Inference in Additive Models and Its Application to Model Undernutrition

可加模型的直接同时推断及营养不足建模应用

This article proposes a simple and fast approach to build simultaneous confidence bands and perform specification tests for smooth curves in additive models. The method allows for handling of spatially heterogeneous functions and its derivatives as well as heteroscedasticity in the data. It is applied to study the determinants of chronic undernutrition of Kenyan children, with a particular focus on the highly nonlinear age pattern in undernutrition. Model estimation using…

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LACK-OF-FIT TESTING OF THE CONDITIONAL MEAN FUNCTION IN A CLASS OF MARKOV MULTIPLICATIVE ERROR MODELS

一类马尔可夫乘法误差模型的条件均值失拟检验

Abstract The family of multiplicative error models, introduced by Engle (2002, Journal of Applied Econometrics 17, 425–446), has attracted considerable attention in recent literature for modeling positive random variables, such as the duration between trades at a stock exchange, volume transactions, and squared log returns. Such models are also applicable to other positive variables such as waiting time in a queue, daily/hourly rainfall, and demand for electricity. This…

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TESTING UNDER WEAK IDENTIFICATION WITH CONDITIONAL MOMENT RESTRICTIONS

条件矩限制下的弱识别稳健检验

Abstract We propose a semiparametric test for the value of coefficients in models with conditional moment restrictions that has correct size regardless of identification strength. The test is in essence an Anderson-Rubin (AR) test using nonparametrically estimated instruments to which we apply a standard error correction. We show that the test is (1) always size-correct, (2) consistent when identification is not too weak, and (3) asymptotically equivalent to an infeasible AR…

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Ordinal Dominance Curve Based Inference for Stochastically Ordered Distributions

基于序数优势曲线的随机有序分布推断

Summary In a variety of applications researchers collect data that are sampled under ordered experimental conditions. In such situations it is reasonable to assume that outcomes are ordered stochastically by the level of the treatment. For example a toxicologist may want to assess the effect of a toxin on the reproductive system by studying the number of offspring produced by an animal as a function of the dose that it received. A variety of scientific questions arise in…

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Semiparametric trending panel data models with cross-sectional dependence

具有截面相关性的半参数趋势面板模型

A semiparametric fixed effects model is introduced to describe the nonlinear trending phenomenon in panel data analysis and it allows for the cross-sectional dependence in both the regressors and the residuals. A pooled semiparametric profile likelihood dummy variable approach based on the first-stage local linear fitting is developed to estimate both the parameter vector and the nonlinear time trend function. As both the time series length T and the cross-sectional size N…

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Higher order properties of the wild bootstrap under misspecification

模型误设下野生自助法的高阶性质

We examine the higher order properties of the wild bootstrap (Wu, 1986) in a linear regression model with stochastic regressors. We find that the ability of the wild bootstrap to provide a higher order refinement is contingent upon whether the errors are mean independent of the regressors or merely uncorrelated with them. In the latter case, the wild bootstrap may fail to match some of the terms in an Edgeworth expansion of the full sample test statistic. Nonetheless, we…

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Nonparametric estimation and inference about the overlap of two distributions

两个分布重叠程度的非参数估计与推断

This paper develops methodology for nonparametric estimation of a measure of the overlap of two distributions based on kernel estimation techniques. This quantity has been proposed as a measure of economic polarization between two groups, Anderson (2004) and Anderson et al. (2010). In ecology it has been used to measure the overlap of species. We give the asymptotic distribution theory of our estimator, which in some cases of practical relevance is nonstandard due to a…

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Nonparametric identification of dynamic models with unobserved state variables

含不可观测状态变量的动态模型的非参数识别

We consider the identification of a Markov process {Wt,Xt∗} when only {Wt} is observed. In structural dynamic models, Wt includes the choice variables and observed state variables of an optimizing agent, while Xt∗ denotes time-varying serially correlated unobserved state variables (or agent-specific unobserved heterogeneity). In the non-stationary case, we show that the Markov law of motion fWt,Xt∗∣Wt−1,Xt−1∗ is identified from five periods of data Wt+1,Wt,Wt−1,Wt−2,Wt−3. In…

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The Variance of Non-Parametric Treatment Effect Estimators in the Presence of Clustering

存在聚类时非参数处理效应估计量的方差

Nonparametric estimators of treatment effects are often applied in settings where clustering may be important. We provide a general methodology for consistently estimating the variance of a large class of nonparametric estimators, including the simple matching estimator, in the presence of clustering. Software for implementing our variance estimator is available in Stata.

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