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Guided Adversarial Robust Transfer Learning with Source Mixing

结合源分布混合的引导式对抗鲁棒迁移学习

Transfer learning is a critical technique that enables the application of knowledge gained from existing tasks or domains to improve performance on a new one, reducing the need for extensive data and training in each new context. Many existing transfer learning methods rely on leveraging information from source populations closely resembling the target population. However, this approach often overlooks valuable knowledge that may be present in different yet potentially…

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Distributionally robust learning for multisource unsupervised domain adaptation

多源无监督域适应的分布鲁棒学习

Empirical risk minimization often performs poorly when the distribution of the target domain differs from those of the source domains. To address such potential distributional shifts, we develop an unsupervised domain adaptation approach that leverages labeled data from multiple source domains and unlabeled data from the target domain. We introduce a distributionally robust model that optimizes an adversarial reward based on explained variance across a class of target…

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Post-selection inference for causal effects after causal discovery

因果发现后因果效应的选择后推断

Summary Algorithms for constraint-based causal discovery select graphical causal models among a space of possible candidates (e.g., all directed acyclic graphs) by executing a sequence of conditional independence tests. These may be used to inform the estimation of causal effects (e.g., average treatment effects) when there is uncertainty about which covariates ought to be adjusted for, or which variables act as confounders versus mediators. However, naively using the data…

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Robust Inference for Federated Meta-Learning

联邦元学习的稳健推断

Synthesizing information from multiple data sources is critical to ensure knowledge generalizability. Integrative analysis of multi-source data is challenging due to the heterogeneity across sources and data-sharing constraints due to privacy concerns. In this paper, we consider a general robust inference framework for federated meta-learning of data from multiple sites, enabling statistical inference for the prevailing model, defined as the one matching the majority of the…

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A Heteroscedasticity-Robust Overidentifying Restriction Test with High-Dimensional Covariates

高维协变量下对异方差稳健的过度识别约束检验

This paper proposes an overidentifying restriction test for high-dimensional linear instrumental variable models. The novelty of the proposed test is that it allows the number of covariates and instruments to be larger than the sample size. The test is scale-invariant and robust to heteroskedastic errors. To construct the final test statistic, we first introduce a test based on the maximum norm of multiple parameters that could be high-dimensional. The theoretical power…

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Statistical Inference for Maximin Effects: Identifying Stable Associations across Multiple Studies

最大最小效应的统计推断:识别跨研究稳定关联

Integrative analysis of data from multiple sources is critical to making generalizable discoveries. Associations consistently observed across multiple source populations are more likely to be generalized to target populations with possible distributional shifts. In this paper, we model the heterogeneous multi-source data with multiple high-dimensional regressions and make inferences for the maximin effect (Meinshausen, Bühlmann, AoS, 43(4), 1801–1830). The maximin effect…

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Causal inference with invalid instruments: post-selection problems and a solution using searching and sampling

无效工具变量下的因果推断:选择后问题及搜索与抽样方案

Abstract Instrumental variable methods are among the most commonly used causal inference approaches to deal with unmeasured confounders in observational studies. The presence of invalid instruments is the primary concern for practical applications, and a fast-growing area of research is inference for the causal effect with possibly invalid instruments. This paper illustrates that the existing confidence intervals may undercover when the valid and invalid instruments are hard…

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Statistical Inference for High-Dimensional Generalized Linear Models With Binary Outcomes

高维二元结局广义线性模型的统计推断

This paper develops a unified statistical inference framework for high-dimensional binary generalized linear models (GLMs) with general link functions. Both unknown and known design distribution settings are considered. A two-step weighted bias-correction method is proposed for constructing confidence intervals and simultaneous hypothesis tests for individual components of the regression vector. Minimax lower bound for the expected length is established and the proposed…

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Doubly debiased lasso: High-dimensional inference under hidden confounding

双重去偏 lasso:隐藏混杂下的高维推断

Inferring causal relationships or related associations from observational data can be invalidated by the existence of hidden confounding. We focus on a high-dimensional linear regression setting, where the measured covariates are affected by hidden confounding and propose the doubly debiased lasso estimator for individual components of the regression coefficient vector. Our advocated method simultaneously corrects both the bias due to estimation of high-dimensional…

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Optimal Statistical Inference for Individualized Treatment Effects in High-Dimensional Models

高维模型中个体化处理效应的最优统计推断

Abstract The ability to predict individualized treatment effects (ITEs) based on a given patient's profile is essential for personalized medicine. We propose a hypothesis testing approach to choosing between two potential treatments for a given individual in the framework of high-dimensional linear models. The methodological novelty lies in the construction of a debiased estimator of the ITE and establishment of its asymptotic normality uniformly for an arbitrary future…

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Semisupervised Inference for Explained Variance in High Dimensional Linear Regression and its Applications

高维线性回归解释方差的半监督推断及其应用

Summary The paper considers statistical inference for the explained variance βTΣβ under the high dimensional linear model Y = Xβ + ε in the semisupervised setting, where β is the regression vector and Σ is the design covariance matrix. A calibrated estimator, which efficiently integrates both labelled and unlabelled data, is proposed. It is shown that the estimator achieves the minimax optimal rate of convergence in the general semisupervised framework. The optimality result…

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Optimal Estimation of Genetic Relatedness in High-Dimensional Linear Models

高维线性模型中遗传关联性的最优估计

Estimating the genetic relatedness between two traits based on the genome-wide association data is an important problem in genetics research. In the framework of high-dimensional linear models, we introduce two measures of genetic relatedness and develop optimal estimators for them. One is genetic covariance, which is defined to be the inner product of the two regression vectors, and another is genetic correlation, which is a normalized inner product by their lengths. We…

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Testing endogeneity with high dimensional covariates

高维协变量下的内生性检验

Modern, high dimensional data has renewed investigation on instrumental variables (IV) analysis, primarily focusing on estimation of effects of endogenous variables and putting little attention towards specification tests. This paper studies in high dimensions the Durbin–Wu–Hausman (DWH) test, a popular specification test for endogeneity in IV regression. We show, surprisingly, that the DWH test maintains its size in high dimensions, but at an expense of power. We propose a…

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Confidence Intervals for Causal Effects with Invalid Instruments by Using Two-Stage Hard Thresholding with Voting

存在无效工具变量时的因果效应置信区间:两阶段硬阈值与投票

Summary A major challenge in instrumental variable (IV) analysis is to find instruments that are valid, or have no direct effect on the outcome and are ignorable. Typically one is unsure whether all of the putative IVs are in fact valid. We propose a general inference procedure in the presence of invalid IVs, called two-stage hard thresholding with voting. The procedure uses two hard thresholding steps to select strong instruments and to generate candidate sets of valid IVs.…

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Accuracy assessment for high-dimensional linear regression

高维线性回归估计的精度评估

This paper considers point and interval estimation of the $\ell_{q}$ loss of an estimator in high-dimensional linear regression with random design. We establish the minimax rate for estimating the $\ell_{q}$ loss and the minimax expected length of confidence intervals for the $\ell_{q}$ loss of rate-optimal estimators of the regression vector, including commonly used estimators such as Lasso, scaled Lasso, square-root Lasso and Dantzig Selector. Adaptivity of confidence…

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Confidence intervals for high-dimensional linear regression: Minimax rates and adaptivity

高维线性回归置信区间的极小极大速率与自适应性

Confidence sets play a fundamental role in statistical inference. In this paper, we consider confidence intervals for high-dimensional linear regression with random design. We first establish the convergence rates of the minimax expected length for confidence intervals in the oracle setting where the sparsity parameter is given. The focus is then on the problem of adaptation to sparsity for the construction of confidence intervals. Ideally, an adaptive confidence interval…

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