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Individualized Dynamic Mediation Analysis Using Latent Factor Models

基于潜在因子模型的个体化动态中介分析

Mediation analysis plays a crucial role in causal inference as it can investigate the pathways through which treatment influences outcome. Most existing mediation analysis assumes that mediation effects are static and homogeneous within populations. However, mediation effects usually change over time and exhibit significant heterogeneity among individuals in many real-world applications. Additionally, the mediation mechanism can be complicated and involves non-sparse, making…

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Optimal Transport based Cross-Domain Integration for Heterogeneous Data

基于最优传输的异质数据跨域整合

Detecting dynamic patterns shared across heterogeneous datasets is a critical yet challenging task in many scientific domains, particularly within the biomedical sciences. Systematic heterogeneity inherent in diverse data sources can significantly hinder the effectiveness of existing machine learning methods in uncovering shared underlying dynamics. Additionally, practical and technical constraints in real-world experimental designs often limit data collection to only a…

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De-confounding Causal Inference Using Latent Multiple-Mediator Pathways

利用潜在多中介路径消除因果推断中的混杂

Causal effect estimation from observational data is one of the essential problems in causal inference. However, most estimation methods rely on the strong assumption that all confounders are observed, which is impractical and untestable in the real world. We develop a mediation analysis framework inferring the latent confounder for debiasing both direct and indirect causal effects. Specifically, we introduce generalized structural equation modeling that incorporates…

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Crowdsourcing Utilizing Subgroup Structure of Latent Factor Modeling

利用潜在因子模型子群结构的众包标注

Crowdsourcing has emerged as an alternative solution for collecting large scale labels. However, the majority of recruited workers are not domain experts, so their contributed labels could be noisy. In this paper, we propose a two-stage model to predict the true labels for multicategory classification tasks in crowdsourcing. In the first stage, we fit the observed labels with a latent factor model and incorporate subgroup structures for both tasks and workers through a…

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High-Order Joint Embedding for Multi-Level Link Prediction

面向多层次连边预测的高阶联合嵌入

Link prediction infers potential links from observed networks, and is one of the essential problems in network analyses. In contrast to traditional graph representation modeling which only predicts two-way pairwise relations, we propose a novel tensor-based joint network embedding approach on simultaneously encoding pairwise links and hyperlinks onto a latent space, which captures the dependency between pairwise and multi-way links in inferring potential unobserved…

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Community detection with dependent connectivity

连接存在依赖时的社区检测

In network analysis, within-community members are more likely to be connected than between-community members, which is reflected in that the edges within a community are intercorrelated. However, existing probabilistic models for community detection such as the stochastic block model (SBM) are not designed to capture the dependence among edges. In this paper, we propose a new community detection approach to incorporate intra-community dependence of connectivities through the…

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