Identifying Genetic Variants for Brain Connectivity Using Ball Covariance Ranking and Aggregation
利用球协方差排序与聚合识别脑连接相关遗传变异
Understanding the genetic architecture of brain functions is essential to clarify the biological etiologies of behavioral and psychiatric disorders. Functional connectivity, representing pairwise correlations of neural activities between brain regions, is moderately heritable. Current methods to identify single nucleotide polymorphisms (SNPs) linked to functional connectivity either neglect the complex structure of functional connectivity or fail to control false…