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Predictions as Surrogates: Revisiting Surrogate Outcomes in the Age of AI

将预测作为替代结果:人工智能时代重新审视替代结局

Abstract We establish a formal connection between the decades-old surrogate outcome model in biostatistics and economics and the emerging field of prediction-powered inference. The connection treats predictions from pre-trained models, prevalent in the age of AI, as cost-effective surrogates for expensive outcomes that are not fully observed. Building on the surrogate outcomes literature, we develop recalibrated prediction-powered inference, a more efficient approach to…

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A flexible defense against the winner’s curse

灵活应对赢家诅咒的推断方法

Across science and policy, decision-makers often need to draw conclusions about the best candidate among competing alternatives. For instance, researchers may seek to infer the effectiveness of the most successful treatment or determine which demographic group benefits most from a specific treatment. Similarly, in machine learning, practitioners are often interested in the population performance of the model that performs best empirically. However, cherry-picking the best…

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Valid Inference After Causal Discovery

因果发现之后的有效推断

Causal discovery and causal effect estimation are two fundamental tasks in causal inference. While many methods have been developed for each task individually, statistical challenges arise when applying these methods jointly: estimating causal effects after running causal discovery algorithms on the same data leads to "double dipping," invalidating the coverage guarantees of classical confidence intervals. To this end, we develop tools for valid post-causal-discovery…

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Locally simultaneous inference

局部同时推断

Selective inference is the problem of giving valid answers to statistical questions chosen in a data-driven manner. A standard solution to selective inference is simultaneous inference, which delivers valid answers to the set of all questions that could possibly have been asked. However, simultaneous inference can be unnecessarily conservative if this set includes many questions that were unlikely to be asked in the first place. We introduce a less conservative solution to…

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Post-selection inference via algorithmic stability

通过算法稳定性进行选择后推断

When the target of statistical inference is chosen in a data-driven manner, the guarantees provided by classical theories vanish. We propose a solution to the problem of inference after selection by building on the framework of algorithmic stability, in particular its branch with origins in the field of differential privacy. Stability is achieved via randomization of selection and it serves as a quantitative measure that is sufficient to obtain nontrivial post-selection…

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