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协变量调整回归函数的去偏推断AI 解读

Abstract In this article, we study nonparametric inference for a covariate-adjusted regression function. This parameter captures the average association between a continuous exposure and an outcome after adjusting for other covariates. Under certain causal conditions, it also corresponds to the average outcome had all units been assigned to a specific exposure level, known as the causal dose–response curve. We propose a debiased local linear estimator of the…

利用机器学习推断处理特定生存曲线AI 解读

In the absence of data from a randomized trial, researchers may aim to use observational data to draw causal inference about the effect of a treatment on a time-to-event outcome. In this context, interest often focuses on the treatment-specific survival curves, that is, the survival curves were the population under study to be assigned to receive the treatment or not. Under certain conditions, including that all confounders of the treatment-outcome relationship are observed,…

非离散暴露下因果零假设的非参数检验AI 解读

In many scientific studies, it is of interest to determine whether an exposure has a causal effect on an outcome. In observational studies, this is a challenging task due to the presence of confounding variables that affect both the exposure and the outcome. Many methods have been developed to test for the presence of a causal effect when all such confounding variables are observed and when the exposure of interest is discrete. In this article, we propose a class of…

因果保序回归AI 解读

Summary In observational studies, potential confounders may distort the causal relationship between an exposure and an outcome. However, under some conditions, a causal dose–response curve can be recovered by using the G-computation formula. Most classical methods for estimating such curves when the exposure is continuous rely on restrictive parametric assumptions, which carry significant risk of model misspecification. Non-parametric estimation in this context is…

单调函数非参数推断的统一研究AI 解读

The problem of nonparametric inference on a monotone function has been extensively studied in many particular cases. Estimators considered have often been of so-called Grenander type, being representable as the left derivative of the greatest convex minorant or least concave majorant of an estimator of a primitive function. In this paper, we provide general conditions for consistency and pointwise convergence in distribution of a class of generalized Grenander-type…